SCOP 1.73: Domain d2g9xa1: 2g9x A:1-298

Lineage for d2g9xa1 (2g9x A:1-298)

1. Root: SCOP 1.73

2. Class d: Alpha and beta proteins (a+b) [53931] (334 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (7 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (61 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein Cyclin-dependent PK, CDK2 [88855] (2 species)
   CMGC group; CDKs subfamily; serine/threonine kinase

7. Species Human (Homo sapiens) [TaxId:9606] [88856] (124 PDB entries)

8. Domain d2g9xa1: 2g9x A:1-298 [134844]
   Other proteins in same PDB: d2g9xb1, d2g9xb2, d2g9xd1, d2g9xd2
   automatically matched to d1vywa_
   complexed with nu5

Details for d2g9xa1

PDB Entry: 2g9x, 2.5 Å

PDB Description: Structure of Thr 160 phosphorylated CDK2/cyclin A in complex with the inhibitor NU6271

PDB Compounds: (A:) Cell division protein kinase 2

SCOP Domain Sequences for d2g9xa1:

Sequence; same for both SEQRES and ATOM records:

>d2g9xa1 d.144.1.7 (A:1-298) Cyclin-dependent PK, CDK2 {Human (Homo sapiens) [TaxId: 9606]}
menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl

Timeline for d2g9xa1:

• d2g9xa1 is new in SCOP 1.73
  
• d2g9xa1 appears in SCOP 1.75
  
• d2g9xa1 appears in the current release, SCOPe 2.08, called d2g9xa2