SCOPe 2.05: Domain d2g3ya1: 2g3y A:73-244

Lineage for d2g3ya1 (2g3y A:73-244)

1. Root: SCOPe 2.05

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (25 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.8: G proteins [52592] (79 proteins)
   core: mixed beta-sheet of 6 strands, order 231456; strand 2 is antiparallel to the rest

6. Protein GTP-binding protein GEM [142289] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [142290] (2 PDB entries)
   Uniprot P55040 73-244

8. Domain d2g3ya1: 2g3y A:73-244 [134574]
   complexed with gdp

Details for d2g3ya1

PDB Entry: 2g3y, 2.4 Å

PDB Description: Crystal structure of the human small GTPase GEM

PDB Compounds: (A:) GTP-binding protein gem

SCOPe Domain Sequences for d2g3ya1:

Sequence, based on SEQRES records:

>d2g3ya1 c.37.1.8 (A:73-244) GTP-binding protein GEM {Human (Homo sapiens) [TaxId: 9606]}
ntyyrvvligeqgvgkstlanifagvhdsmdsdcevlgedtyertlmvdgesatiilldm
wenkgenewlhdhcmqvgdaylivysitdrasfekaselriqlrrarqtedipiilvgnk
sdlvrcrevsvsegracavvfdckfietsaavqhnvkelfegivrqvrlrrd

Sequence, based on observed residues (ATOM records):

>d2g3ya1 c.37.1.8 (A:73-244) GTP-binding protein GEM {Human (Homo sapiens) [TaxId: 9606]}
ntyyrvvligeqgvgkstlanifagvhdsmdsdlgedtyertlmvdgesatiilldmwen
kgenewlhdhcmqvgdaylivysitdrasfekaselriqlrrarqtedipiilvgnksdl
vrcrevsvsegracavvfdckfietsaavqhnvkelfegivrqvrlrrd

Timeline for d2g3ya1:

• d2g3ya1 first appeared in SCOP 1.73
  
• d2g3ya1 appears in SCOPe 2.04
  
• d2g3ya1 appears in SCOPe 2.06
  
• d2g3ya1 appears in the current release, SCOPe 2.08