SCOP 1.75: Domain d2g00l1: 2g00 L:87-138

Lineage for d2g00l1 (2g00 L:87-138)

1. Root: SCOP 1.75

2. Class g: Small proteins [56992] (90 folds)

3. Fold g.3: Knottins (small inhibitors, toxins, lectins) [57015] (19 superfamilies)
   disulfide-bound fold; contains beta-hairpin with two adjacent disulfides

4. Superfamily g.3.11: EGF/Laminin [57196] (7 families)

5. Family g.3.11.1: EGF-type module [57197] (22 proteins)

6. Protein Factor X, N-terminal module [57205] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [57206] (74 PDB entries)
   Uniprot P00742 127-178

8. Domain d2g00l1: 2g00 L:87-138 [134489]
   Other proteins in same PDB: d2g00a1
   automatically matched to d1g2lb_
   complexed with 4qc

Details for d2g00l1

PDB Entry: 2g00, 2.1 Å

PDB Description: factor xa in complex with the inhibitor 3-(6-(2'-((dimethylamino) methyl)-4-biphenylyl)-7-oxo-3-(trifluoromethyl)-4,5,6,7-tetrahydro- 1h-pyrazolo[3,4-c]pyridin-1-yl)benzamide

PDB Compounds: (L:) coagulation factor x

SCOP Domain Sequences for d2g00l1:

Sequence; same for both SEQRES and ATOM records:

>d2g00l1 g.3.11.1 (L:87-138) Factor X, N-terminal module {Human (Homo sapiens) [TaxId: 9606]}
klcsldngdcdqfcheeqnsvvcscargytladngkaciptgpypcgkqtle

Timeline for d2g00l1:

• d2g00l1 first appeared in SCOP 1.73
  
• d2g00l1 is called d2g00l_ in SCOPe 2.01
  
• d2g00l1 appears in the current release, SCOPe 2.08, called d2g00l_