SCOPe 2.02: Domain d2fzzl_: 2fzz L:

Lineage for d2fzzl_ (2fzz L:)

1. Root: SCOPe 2.02

2. Class g: Small proteins [56992] (90 folds)

3. Fold g.3: Knottins (small inhibitors, toxins, lectins) [57015] (19 superfamilies)
   disulfide-bound fold; contains beta-hairpin with two adjacent disulfides

4. Superfamily g.3.11: EGF/Laminin [57196] (7 families)

5. Family g.3.11.1: EGF-type module [57197] (23 proteins)

6. Protein automated matches [190092] (1 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187310] (52 PDB entries)

8. Domain d2fzzl_: 2fzz L: [134487]
   Other proteins in same PDB: d2fzza_
   automated match to d1g2lb_
   complexed with 5qc

Details for d2fzzl_

PDB Entry: 2fzz, 2.2 Å

PDB Description: Factor Xa in complex with the inhibitor 1-(3-amino-1,2-benzisoxazol-5-yl)-6-(2'-(((3r)-3-hydroxy-1-pyrrolidinyl)methyl)-4-biphenylyl)-3-(trifluoromethyl)-1,4,5,6-tetrahydro-7h-pyrazolo[3,4-c]pyridin-7-one

PDB Compounds: (L:) coagulation factor x

SCOPe Domain Sequences for d2fzzl_:

Sequence; same for both SEQRES and ATOM records:

>d2fzzl_ g.3.11.1 (L:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
klcsldngdcdqfcheeqnsvvcscargytladngkaciptgpypcgkqtle

Timeline for d2fzzl_:

• d2fzzl_ first appeared in SCOP 1.73, called d2fzzl1
  
• d2fzzl_ appears in SCOPe 2.01
  
• d2fzzl_ appears in SCOPe 2.03
  
• d2fzzl_ appears in the current release, SCOPe 2.08