Lineage for d2fzza1 (2fzz A:16-244)

  1. Root: SCOP 1.73
  2. 651986Class b: All beta proteins [48724] (165 folds)
  3. 670182Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
    barrel, closed; n=6, S=8; greek-key
    duplication: consists of two domains of the same fold
  4. 670183Superfamily b.47.1: Trypsin-like serine proteases [50494] (4 families) (S)
  5. 670328Family b.47.1.2: Eukaryotic proteases [50514] (47 proteins)
  6. 670527Protein Coagulation factor Xa, protease domain [50574] (2 species)
  7. 670530Species Human (Homo sapiens) [TaxId:9606] [50575] (58 PDB entries)
  8. 670565Domain d2fzza1: 2fzz A:16-244 [134486]
    Other proteins in same PDB: d2fzzl1
    automatically matched to d1c5md_
    complexed with 5qc

Details for d2fzza1

PDB Entry: 2fzz (more details), 2.2 Å

PDB Description: Factor Xa in complex with the inhibitor 1-(3-amino-1,2-benzisoxazol-5-yl)-6-(2'-(((3r)-3-hydroxy-1-pyrrolidinyl)methyl)-4-biphenylyl)-3-(trifluoromethyl)-1,4,5,6-tetrahydro-7h-pyrazolo[3,4-c]pyridin-7-one
PDB Compounds: (A:) coagulation factor x

SCOP Domain Sequences for d2fzza1:

Sequence; same for both SEQRES and ATOM records: (download)

>d2fzza1 b.47.1.2 (A:16-244) Coagulation factor Xa, protease domain {Human (Homo sapiens) [TaxId: 9606]}
ivggqeckdgecpwqallineenegfcggtilsefyiltaahclyqakrfkvrvgdrnte
qeeggeavhevevvikhnrftketydfdiavlrlktpitfrmnvapaclperdwaestlm
tqktgivsgfgrthekgrqstrlkmlevpyvdrnscklsssfiitqnmfcagydtkqeda
cqgdsggphvtrfkdtyfvtgivswgegcarkgkygiytkvtaflkwidrsmkt

SCOP Domain Coordinates for d2fzza1:

Click to download the PDB-style file with coordinates for d2fzza1.
(The format of our PDB-style files is described here.)

Timeline for d2fzza1: