SCOP 1.73: Domain d2fysb1: 2fys B:8-356

Lineage for d2fysb1 (2fys B:8-356)

1. Root: SCOP 1.73

2. Class d: Alpha and beta proteins (a+b) [53931] (334 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (7 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (61 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein MAP kinase Erk2 [56134] (2 species)
   CMGC group; ERK/MAPK subfamily; serine/threonine kinase

7. Species Rat (Rattus norvegicus) [TaxId:10116] [56136] (6 PDB entries)

8. Domain d2fysb1: 2fys B:8-356 [134390]
   automatically matched to d1erk__

Details for d2fysb1

PDB Entry: 2fys, 2.5 Å

PDB Description: Crystal structure of Erk2 complex with KIM peptide derived from MKP3

PDB Compounds: (B:) Mitogen-activated protein kinase 1

SCOP Domain Sequences for d2fysb1:

Sequence, based on SEQRES records:

>d2fysb1 d.144.1.7 (B:8-356) MAP kinase Erk2 {Rat (Rattus norvegicus) [TaxId: 10116]}
gpemvrgqvfdvgprytnlsyigegaygmvcsaydnlnkvrvaikkispfehqtycqrtl
reikillrfrheniigindiiraptieqmkdvyivqdlmetdlykllktqhlsndhicyf
lyqilrglkyihsanvlhrdlkpsnlllnttcdlkicdfglarvadpdhdhtgflteyva
trwyrapeimlnskgytksidiwsvgcilaemlsnrpifpgkhyldqlnhilgilgspsq
edlnciinlkarnyllslphknkvpwnrlfpnadskaldlldkmltfnphkrieveqala
hpyleqyydpsdepiaeapfkfdmelddlpkeklkelifeetarfqpgy

Sequence, based on observed residues (ATOM records):

>d2fysb1 d.144.1.7 (B:8-356) MAP kinase Erk2 {Rat (Rattus norvegicus) [TaxId: 10116]}
gpemvrgqvfdvgprytnlsyigegaygmvcsaydnlnkvrvaikkispfehqtycqrtl
reikillrfrheniigindiiraptieqmkdvyivqdlmetdlykllktqhlsndhicyf
lyqilrglkyihsanvlhrdlkpsnlllnttcdlkicdfglarvadpdeyvatrwyrape
imlnskgytksidiwsvgcilaemlsnrpifpgkhyldqlnhilgilgspsqedlnciin
lkarnyllslphknkvpwnrlfpnadskaldlldkmltfnphkrieveqalahpyleqyy
dpsdepiaeapfklddlpkeklkelifeetarfqpgy

Timeline for d2fysb1:

• d2fysb1 is new in SCOP 1.73
  
• d2fysb1 appears in SCOP 1.75
  
• d2fysb1 appears in the current release, SCOPe 2.08, called d2fysb_