Lineage for d2fx7h1 (2fx7 H:1-113)

  1. Root: SCOP 1.75
  2. 781541Class b: All beta proteins [48724] (174 folds)
  3. 781542Fold b.1: Immunoglobulin-like beta-sandwich [48725] (28 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 781543Superfamily b.1.1: Immunoglobulin [48726] (4 families) (S)
  5. 781544Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (32 proteins)
  6. 781740Protein Immunoglobulin heavy chain variable domain, VH [88543] (22 species)
    VH domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VH domains with artificial or grafted exogenous CDRs are listed as engineered species
  7. 781850Species Human (Homo sapiens), cluster 1 [TaxId:9606] [88544] (36 PDB entries)
  8. 781852Domain d2fx7h1: 2fx7 H:1-113 [134276]
    Other proteins in same PDB: d2fx7h2, d2fx7l1, d2fx7l2
    automatically matched to d1hzhh1
    complexed with gol; mutant

Details for d2fx7h1

PDB Entry: 2fx7 (more details), 1.76 Å

PDB Description: crystal structure of hiv-1 neutralizing human fab 4e10 in complex with a 16-residue peptide encompassing the 4e10 epitope on gp41
PDB Compounds: (H:) Fab 4E10

SCOP Domain Sequences for d2fx7h1:

Sequence; same for both SEQRES and ATOM records: (download)

>d2fx7h1 b.1.1.1 (H:1-113) Immunoglobulin heavy chain variable domain, VH {Human (Homo sapiens), cluster 1 [TaxId: 9606]}

SCOP Domain Coordinates for d2fx7h1:

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(The format of our PDB-style files is described here.)

Timeline for d2fx7h1:

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