SCOP 1.73: Domain d2fvmd2: 2fvm D:57-440

Lineage for d2fvmd2 (2fvm D:57-440)

1. Root: SCOP 1.73

2. Class c: Alpha and beta proteins (a/b) [51349] (141 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.9: Metallo-dependent hydrolases [51556] (15 families)
   the beta-sheet barrel is similarly distorted and capped by a C-terminal helix
   has transition metal ions bound inside the barrel

5. Family c.1.9.6: Hydantoinase (dihydropyrimidinase), catalytic domain [75073] (5 proteins)

6. Protein Dihydropyrimidine amidohydrolase Pyd2 [141805] (2 species)

7. Species Yeast (Saccharomyces kluyveri) [TaxId:4934] [141806] (3 PDB entries)

8. Domain d2fvmd2: 2fvm D:57-440 [134219]
   Other proteins in same PDB: d2fvma1, d2fvmb1, d2fvmc1, d2fvmd1
   automatically matched to 2FTY A:57-440
   complexed with urp, zn

Details for d2fvmd2

PDB Entry: 2fvm, 2.45 Å

PDB Description: Crystal structure of dihydropyrimidinase from Saccharomyces kluyveri in complex with the reaction product N-carbamyl-beta-alanine

PDB Compounds: (D:) dihydropyrimidinase

SCOP Domain Sequences for d2fvmd2:

Sequence, based on SEQRES records:

>d2fvmd2 c.1.9.6 (D:57-440) Dihydropyrimidine amidohydrolase Pyd2 {Yeast (Saccharomyces kluyveri) [TaxId: 4934]}
ggidahvhvdeplkllgdvvdtmehatrsavaggtttvvafstqdvskkgpsalaesvkl
dvdeyseqtlycdyglhlilfqiekpsvearelldvqlqaayndygvssvkmfmtypglq
isdydimsamyatrkngfttmlhaengdmvkwmiealeeqgltdayyhgvsrpsivegea
tnraitlattmdtpilfvhvsspqaaevikqaqtkglkvyaetcpqyallsdaitrchhh
gevesygvgidlssisespftnpddrfigskyicsppirpegtqksiwkgmnngtftivg
sdhcsynyyektstaskhrafdpennkngefryipnglpgvctrmpllydygylrgnlts
mmklveiqctnpakvygmypqkgs

Sequence, based on observed residues (ATOM records):

>d2fvmd2 c.1.9.6 (D:57-440) Dihydropyrimidine amidohydrolase Pyd2 {Yeast (Saccharomyces kluyveri) [TaxId: 4934]}
ggidahvhvdeplkllgdvvdtmehatrsavaggtttvvafstqdvskkgpsalaesvkl
dvdeyseqtlycdyglhlilfqiekpsvearelldvqlqaayndygvssvkmfmtypglq
isdydimsamyatrkngfttmlhaengdmvkwmiealeeqgltdayyhgvsrpsivegea
tnraitlattmdtpilfvhvsspqaaevikqaqtkglkvyaetcpqyallsdaitrchvg
idlssisespftnpddrfigskyicsppirpegtqksiwkgmnngtftivgsdhcsynyy
ektstaskhrafdpennkngefryipnglpgvctrmpllydygylrgnltsmmklveiqc
tnpakvygmypqkgs

Timeline for d2fvmd2:

• d2fvmd2 is new in SCOP 1.73
  
• d2fvmd2 appears in SCOP 1.75
  
• d2fvmd2 appears in the current release, SCOPe 2.08