SCOPe 2.05: Domain d2fsvc1: 2fsv C:30-203

Lineage for d2fsvc1 (2fsv C:30-203)

1. Root: SCOPe 2.05

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.31: DHS-like NAD/FAD-binding domain [52466] (1 superfamily)
   3 layers: a/b/a; parallel beta-sheet of 6 strands, order 321456; Rossmann-like

4. Superfamily c.31.1: DHS-like NAD/FAD-binding domain [52467] (7 families)
   binds cofactor molecules in the opposite direction than classical Rossmann fold

5. Family c.31.1.4: Transhydrogenase domain III (dIII) [52484] (2 proteins)
   binds NADP, shares with the pyruvate oxidase FAD-binding domain a common ADP-binding mode
   automatically mapped to Pfam PF02233

6. Protein Transhydrogenase domain III (dIII) [52485] (3 species)

7. Species Rhodospirillum rubrum [TaxId:1085] [52488] (15 PDB entries)

8. Domain d2fsvc1: 2fsv C:30-203 [134041]
   Other proteins in same PDB: d2fsva1, d2fsva2, d2fsvb1, d2fsvb2
   complexed with gol, nad, nap

Details for d2fsvc1

PDB Entry: 2fsv, 2.3 Å

PDB Description: structure of transhydrogenase (di.d135n.nad+)2(diii.e155w.nadp+)1 asymmetric complex

PDB Compounds: (C:) NAD(P) transhydrogenase subunit beta

SCOPe Domain Sequences for d2fsvc1:

Sequence; same for both SEQRES and ATOM records:

>d2fsvc1 c.31.1.4 (C:30-203) Transhydrogenase domain III (dIII) {Rhodospirillum rubrum [TaxId: 1085]}
svkagsaedaafimknaskviivpgygmavaqaqhalremadvlkkegvevsyaihpvag
rmpghmnvllaeanvpydevfeleeinssfqtadvafvigandvtnpaaktdpsspiygm
pildvwkagtvlfikrsmasgyagvenelffrnntmmlfgdakkmteqivqamn

Timeline for d2fsvc1:

• d2fsvc1 first appeared in SCOP 1.73
  
• d2fsvc1 appears in SCOPe 2.04
  
• d2fsvc1 appears in SCOPe 2.06
  
• d2fsvc1 appears in the current release, SCOPe 2.08