SCOPe 2.08: Domain d2fr8c_: 2fr8 C:

Lineage for d2fr8c_ (2fr8 C:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.31: DHS-like NAD/FAD-binding domain [52466] (1 superfamily)
   3 layers: a/b/a; parallel beta-sheet of 6 strands, order 321456; Rossmann-like

4. Superfamily c.31.1: DHS-like NAD/FAD-binding domain [52467] (7 families)
   binds cofactor molecules in the opposite direction than classical Rossmann fold

5. Family c.31.1.4: Transhydrogenase domain III (dIII) [52484] (2 proteins)
   binds NADP, shares with the pyruvate oxidase FAD-binding domain a common ADP-binding mode
   automatically mapped to Pfam PF02233

6. Protein Transhydrogenase domain III (dIII) [52485] (3 species)

7. Species Rhodospirillum rubrum [TaxId:1085] [52488] (15 PDB entries)

8. Domain d2fr8c_: 2fr8 C: [133977]
   Other proteins in same PDB: d2fr8a1, d2fr8a2, d2fr8b1, d2fr8b2
   automated match to d1nm5c_
   complexed with nad, nap

Details for d2fr8c_

PDB Entry: 2fr8, 2.6 Å

PDB Description: structure of transhydrogenase (di.r127a.nad+)2(diii.nadp+)1 asymmetric complex

PDB Compounds: (C:) NAD(P) transhydrogenase subunit beta

SCOPe Domain Sequences for d2fr8c_:

Sequence; same for both SEQRES and ATOM records:

>d2fr8c_ c.31.1.4 (C:) Transhydrogenase domain III (dIII) {Rhodospirillum rubrum [TaxId: 1085]}
svkagsaedaafimknaskviivpgygmavaqaqhalremadvlkkegvevsyaihpvag
rmpghmnvllaeanvpydevfeleeinssfqtadvafvigandvtnpaaktdpsspiygm
pildvekagtvlfikrsmasgyagvenelffrnntmmlfgdakkmteqivqamn

Timeline for d2fr8c_:

• d2fr8c_ first appeared in SCOP 1.73, called d2fr8c1
  
• d2fr8c_ appears in SCOPe 2.07