SCOPe 2.06: Domain d2fo1a2: 2fo1 A:196-380

Lineage for d2fo1a2 (2fo1 A:196-380)

1. Root: SCOPe 2.06

2. Class b: All beta proteins [48724] (177 folds)

3. Fold b.2: Common fold of diphtheria toxin/transcription factors/cytochrome f [49379] (9 superfamilies)
   sandwich; 9 strands in 2 sheet; greek-key; subclass of immunoglobin-like fold

4. Superfamily b.2.5: p53-like transcription factors [49417] (8 families)

5. Family b.2.5.8: DNA-binding protein LAG-1 (CSL) [110080] (1 protein)

6. Protein DNA-binding protein LAG-1 (CSL) [110081] (1 species)

7. Species Nematode (Caenorhabditis elegans) [TaxId:6239] [110082] (4 PDB entries)
   Uniprot Q9TYY1 195-660

8. Domain d2fo1a2: 2fo1 A:196-380 [133866]
   Other proteins in same PDB: d2fo1a1, d2fo1a3, d2fo1d1, d2fo1e1
   automatically matched to d1ttua2
   protein/DNA complex

Details for d2fo1a2

PDB Entry: 2fo1, 3.12 Å

PDB Description: Crystal Structure of the CSL-Notch-Mastermind ternary complex bound to DNA

PDB Compounds: (A:) Lin-12 and glp-1 phenotype protein 1, isoform b

SCOPe Domain Sequences for d2fo1a2:

Sequence, based on SEQRES records:

>d2fo1a2 b.2.5.8 (A:196-380) DNA-binding protein LAG-1 (CSL) {Nematode (Caenorhabditis elegans) [TaxId: 6239]}
qsltsdrmidflsnkekyecvisifhakvaqksygnekrffcpppciyligqgwklkkdr
vaqlyktlkasaqkdaaiendpiheqqatelvayigigsdtserqqldfstgkvrhpgdq
rqdpniydycaaktlyisdsdkrkyfdlnaqffygcgmeiggfvsqrikviskpskkkqs
mkntd

Sequence, based on observed residues (ATOM records):

>d2fo1a2 b.2.5.8 (A:196-380) DNA-binding protein LAG-1 (CSL) {Nematode (Caenorhabditis elegans) [TaxId: 6239]}
qsltsdrmidflsnkekyecvisifhakvaqksygnekrffcpppciyligqgwklkkdr
vaqlyktlkasaiheqqatelvayigigsdtserqqldfstgkvrhpniydycaaktlyi
sdsdkrkyfdlnaqffygcgmeiggfvsqrikviskpskkd

Timeline for d2fo1a2:

• d2fo1a2 first appeared in SCOP 1.73
  
• d2fo1a2 appears in SCOPe 2.05
  
• d2fo1a2 appears in SCOPe 2.07
  
• d2fo1a2 appears in the current release, SCOPe 2.08