SCOPe 2.08: Domain d2fmua1: 2fmu A:7-236

Lineage for d2fmua1 (2fmu A:7-236)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families)

5. Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (73 proteins)
   also known as short-chain dehydrogenases and SDR family
   parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7
   has additional subdomain(s) that are not in the common domain
   

6. Protein TAT-interacting protein TIP30 [141904] (2 species)

7. Species Mouse (Mus musculus) [TaxId:10090] [141906] (1 PDB entry)
   Uniprot Q9Z2G9 7-236

8. Domain d2fmua1: 2fmu A:7-236 [133795]
   Other proteins in same PDB: d2fmua2
   complexed with edo

Details for d2fmua1

PDB Entry: 2fmu, 2.3 Å

PDB Description: crystal structure of a tat-interacting protein homologue (htatip2, aw111545, cc3, tip30) from mus musculus at 2.30 a resolution

PDB Compounds: (A:) HIV-1 tat interactive protein 2, 30 kDa homolog

SCOPe Domain Sequences for d2fmua1:

Sequence, based on SEQRES records:

>d2fmua1 c.2.1.2 (A:7-236) TAT-interacting protein TIP30 {Mouse (Mus musculus) [TaxId: 10090]}
lpklredfkmqnksvfilgasgetgkvllkeilgqnlfskvtligrrkltfeeeayknvn
qevvdfekldvyasafqghdvgfcclgttrskagaegfvrvdrdyvlksaelakaggckh
fnllssrgadksssflylqvkgeveakveelkfdrlsvfrpgvllcdrqesrpgewlark
ffgslpdswasgyavpvvtvvramlnnlvspssgqmellenkailhlgkd

Sequence, based on observed residues (ATOM records):

>d2fmua1 c.2.1.2 (A:7-236) TAT-interacting protein TIP30 {Mouse (Mus musculus) [TaxId: 10090]}
lpklredfkmqnksvfilgasgetgkvllkeilgqnlfskvtligrrkltfyknvnqevv
dfekldvyasafqghdvgfcclgtkagaegfvrvdrdyvlksaelakaggckhfnllssr
gadksssflylqvkgeveakveelkfdrlsvfrpgvllcdswasgyavpvvtvvramlnn
lvspssgqmellenkailhlgkd

Timeline for d2fmua1:

• d2fmua1 first appeared in SCOP 1.73
  
• d2fmua1 appears in SCOPe 2.07