SCOP 1.73: Domain d2fmeb1: 2fme B:18-362

Lineage for d2fmeb1 (2fme B:18-362)

1. Root: SCOP 1.73

2. Class c: Alpha and beta proteins (a/b) [51349] (141 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (24 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.9: Motor proteins [52641] (4 proteins)

6. Protein Kinesin [52646] (7 species)

7. Species Human (Homo sapiens), mitotic kinesin eg5 [TaxId:9606] [64018] (14 PDB entries)

8. Domain d2fmeb1: 2fme B:18-362 [133772]
   automatically matched to d1q0bb_
   complexed with 3qc, adp, mg

Details for d2fmeb1

PDB Entry: 2fme, 2.1 Å

PDB Description: crystal structure of the mitotic kinesin eg5 (ksp) in complex with mg- adp and (r)-4-(3-hydroxyphenyl)-n,n,7,8-tetramethyl-3,4- dihydroisoquinoline-2(1h)-carboxamide

PDB Compounds: (B:) Kinesin-like protein KIF11

SCOP Domain Sequences for d2fmeb1:

Sequence, based on SEQRES records:

>d2fmeb1 c.37.1.9 (B:18-362) Kinesin {Human (Homo sapiens), mitotic kinesin eg5 [TaxId: 9606]}
niqvvvrcrpfnlaerkasahsivecdpvrkevsvrtggladkssrktytfdmvfgastk
qidvyrsvvcpildevimgynctifaygqtgtgktftmegerspneeytweedplagiip
rtlhqifekltdngtefsvkvslleiyneelfdllnpssdvserlqmfddprnkrgviik
gleeitvhnkdevyqilekgaakrttaatlmnayssrshsvfsvtihmkettidgeelvk
igklnlvdlagsenigrsgavdkrareagninqslltlgrvitalvertphvpyresklt
rilqdslggrtrtsiiatispaslnleetlstleyahraknilnk

Sequence, based on observed residues (ATOM records):

>d2fmeb1 c.37.1.9 (B:18-362) Kinesin {Human (Homo sapiens), mitotic kinesin eg5 [TaxId: 9606]}
niqvvvrcrpfnlaerkasahsivecdpvrkevsvrtggssrktytfdmvfgastkqidv
yrsvvcpildevimgynctifaygqtgtgktftmegerspneeytweedplagiiprtlh
qifekltdngtefsvkvslleiyneelfdllnpssdvserlqmfddprnkrgviikglee
itvhnkdevyqilekgaakrttaatlmnayssrshsvfsvtihmkettidgeelvkigkl
nlvdlagsenigrinqslltlgrvitalvertphvpyreskltrilqdslggrtrtsiia
tispaslnleetlstleyahraknilnk

Timeline for d2fmeb1:

• d2fmeb1 is new in SCOP 1.73
  
• d2fmeb1 appears in SCOP 1.75
  
• d2fmeb1 appears in the current release, SCOPe 2.08, called d2fmeb_