SCOPe 2.07: Domain d2flrh_: 2flr H:

Lineage for d2flrh_ (2flr H:)

1. Root: SCOPe 2.07

2. Class b: All beta proteins [48724] (178 folds)

3. Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
   barrel, closed; n=6, S=8; greek-key
   duplication: consists of two domains of the same fold

4. Superfamily b.47.1: Trypsin-like serine proteases [50494] (5 families)

5. Family b.47.1.2: Eukaryotic proteases [50514] (49 proteins)

6. Protein Coagulation factor VIIa [50550] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [50551] (89 PDB entries)
   Uniprot P08709 213-466 ! Uniprot P08709 213-446

8. Domain d2flrh_: 2flr H: [133747]
   Other proteins in same PDB: d2flrl1, d2flrl2, d2flrt1, d2flrt2
   automated match to d1cvwh_
   complexed with 7nh

Details for d2flrh_

PDB Entry: 2flr, 2.35 Å

PDB Description: novel 5-azaindole factor viia inhibitors

PDB Compounds: (H:) Coagulation factor VII

SCOPe Domain Sequences for d2flrh_:

Sequence; same for both SEQRES and ATOM records:

>d2flrh_ b.47.1.2 (H:) Coagulation factor VIIa {Human (Homo sapiens) [TaxId: 9606]}
ivggkvcpkgecpwqvlllvngaqlcggtlintiwvvsaahcfdkiknwrnliavlgehd
lsehdgdeqsrrvaqviipstyvpgttnhdiallrlhqpvvltdhvvplclpertfsert
lafvrfslvsgwgqlldrgatalelmvlnvprlmtqdclqqsrkvgdspniteymfcagy
sdgskdsckgdsggphathyrgtwyltgivswgqgcatvghfgvytrvsqyiewlqklmr
seprpgvllrapfp

Timeline for d2flrh_:

• d2flrh_ first appeared in SCOP 1.73, called d2flrh1
  
• d2flrh_ appears in SCOPe 2.06
  
• d2flrh_ appears in the current release, SCOPe 2.08