SCOPe 2.01: Domain d2flma_: 2flm A:

Lineage for d2flma_ (2flm A:)

1. Root: SCOPe 2.01

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.3: Prealbumin-like [49451] (7 superfamilies)
   sandwich; 7 strands in 2 sheets, greek-key
   variations: some members have additional 1-2 strands to common fold

4. Superfamily b.3.4: Transthyretin (synonym: prealbumin) [49472] (2 families)

5. Family b.3.4.1: Transthyretin (synonym: prealbumin) [49473] (2 proteins)

6. Protein Transthyretin (synonym: prealbumin) [49474] (5 species)
   sandwich; 8 strands in 2 sheets

7. Species Human (Homo sapiens) [TaxId:9606] [49475] (141 PDB entries)
   Uniprot P02766 31-143

8. Domain d2flma_: 2flm A: [133729]
   automated match to d1eta1_
   complexed with 6ca

Details for d2flma_

PDB Entry: 2flm, 1.65 Å

PDB Description: Human transthyretin (TTR) complexed with bivalant amyloid inhibitor (6 carbon linker)

PDB Compounds: (A:) Transthyretin

SCOPe Domain Sequences for d2flma_:

Sequence; same for both SEQRES and ATOM records:

>d2flma_ b.3.4.1 (A:) Transthyretin (synonym: prealbumin) {Human (Homo sapiens) [TaxId: 9606]}
cplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltteeefvegiy
kveidtksywkalgispfhehaevvftandsgprrytiaallspysysttavvtn

Timeline for d2flma_:

• d2flma_ first appeared in SCOP 1.73, called d2flma1
  
• d2flma_ was called d2flma1 in SCOP 1.75
  
• d2flma_ appears in SCOPe 2.02
  
• d2flma_ appears in the current release, SCOPe 2.08