Lineage for d2flbh_ (2flb H:)

  1. Root: SCOPe 2.01
  2. 929298Class b: All beta proteins [48724] (174 folds)
  3. 952974Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
    barrel, closed; n=6, S=8; greek-key
    duplication: consists of two domains of the same fold
  4. 952975Superfamily b.47.1: Trypsin-like serine proteases [50494] (5 families) (S)
  5. 953177Family b.47.1.2: Eukaryotic proteases [50514] (48 proteins)
  6. 953366Protein Coagulation factor VIIa [50550] (1 species)
  7. 953367Species Human (Homo sapiens) [TaxId:9606] [50551] (28 PDB entries)
    Uniprot P08709 213-466 ! Uniprot P08709 213-446
  8. 953376Domain d2flbh_: 2flb H: [133710]
    Other proteins in same PDB: d2flbt1, d2flbt2
    automated match to d1cvwh_
    complexed with 6nh

Details for d2flbh_

PDB Entry: 2flb (more details), 1.95 Å

PDB Description: discovery of a novel hydroxy pyrazole based factor ixa inhibitor
PDB Compounds: (H:) Coagulation factor VII

SCOPe Domain Sequences for d2flbh_:

Sequence; same for both SEQRES and ATOM records: (download)

>d2flbh_ b.47.1.2 (H:) Coagulation factor VIIa {Human (Homo sapiens) [TaxId: 9606]}
ivggkvcpkgecpwqvlllvngaqlcggtlintiwvvsaahcfdkiknwrnliavlgehd
lsehdgdeqsrrvaqviipstyvpgttnhdiallrlhqpvvltdhvvplclpertfsert
lafvrfslvsgwgqlldrgatalelmvlnvprlmtqdclqqsrkvgdspniteymfcagy
sdgskdsckgdsggphathyrgtwyltgivswgqgcatvghfgvytrvsqyiewlqklmr
seprpgvllrapfp

SCOPe Domain Coordinates for d2flbh_:

Click to download the PDB-style file with coordinates for d2flbh_.
(The format of our PDB-style files is described here.)

Timeline for d2flbh_: