SCOPe 2.08: Domain d2fl2a_: 2fl2 A:

Lineage for d2fl2a_ (2fl2 A:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (27 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.9: Motor proteins [52641] (5 proteins)

6. Protein automated matches [190129] (6 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187145] (33 PDB entries)

8. Domain d2fl2a_: 2fl2 A: [133704]
   automated match to d1q0bb_
   complexed with adp, mg, n4t

Details for d2fl2a_

PDB Entry: 2fl2, 2.5 Å

PDB Description: crystal structure of KSP in complex with inhibitor 19

PDB Compounds: (A:) Kinesin-like protein KIF11

SCOPe Domain Sequences for d2fl2a_:

Sequence, based on SEQRES records:

>d2fl2a_ c.37.1.9 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
niqvvvrcrpfnlaerkasahsivecdpvrkevsvrtggladkssrktytfdmvfgastk
qidvyrsvvcpildevimgynctifaygqtgtgktftmegerspneeytweedplagiip
rtlhqifekltdngtefsvkvslleiyneelfdllnpssdvserlqmfddprnkrgviik
gleeitvhnkdevyqilekgaakrttaatlmnayssrshsvfsvtihmkettidgeelvk
igklnlvdlagsenigrsgavdkrareagninqslltlgrvitalvertphvpyresklt
rilqdslggrtrtsiiatispaslnleetlstleyahraknilnk

Sequence, based on observed residues (ATOM records):

>d2fl2a_ c.37.1.9 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
niqvvvrcrpfnlaerkasahsivecdpvrkevsvrtggladkssrktytfdmvfgastk
qidvyrsvvcpildevimgynctifaygqtgtgktftmegerspneeytweedplagiip
rtlhqifekltdngtefsvkvslleiyneelfdllnpssdvserlqmfddprnkrgviik
gleeitvhnkdevyqilekgaakrttaatlmnayssrshsvfsvtihmkettidgeelvk
igklnlvdlagsenninqslltlgrvitalvertphvpyreskltrilqdslggrtrtsi
iatispaslnleetlstleyahraknilnk

Timeline for d2fl2a_:

• d2fl2a_ first appeared in SCOP 1.73, called d2fl2a1
  
• d2fl2a_ appears in SCOPe 2.07