SCOPe 2.07: Domain d2firh_: 2fir H:

Lineage for d2firh_ (2fir H:)

1. Root: SCOPe 2.07

2. Class b: All beta proteins [48724] (178 folds)

3. Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
   barrel, closed; n=6, S=8; greek-key
   duplication: consists of two domains of the same fold

4. Superfamily b.47.1: Trypsin-like serine proteases [50494] (5 families)

5. Family b.47.1.2: Eukaryotic proteases [50514] (49 proteins)

6. Protein Coagulation factor VIIa [50550] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [50551] (89 PDB entries)
   Uniprot P08709 213-466 ! Uniprot P08709 213-446

8. Domain d2firh_: 2fir H: [133531]
   Other proteins in same PDB: d2firl1, d2firl2, d2firl3, d2firt1, d2firt2
   automated match to d1cvwh_
   complexed with 0g7, ca, cl, fuc, glc, mg, na, zn

Details for d2firh_

PDB Entry: 2fir, 2 Å

PDB Description: crystal structure of dfpr-viia/stf

PDB Compounds: (H:) Coagulation factor VII Heavy Chain (EC 3.4.21.21)

SCOPe Domain Sequences for d2firh_:

Sequence; same for both SEQRES and ATOM records:

>d2firh_ b.47.1.2 (H:) Coagulation factor VIIa {Human (Homo sapiens) [TaxId: 9606]}
ivggkvcpkgecpwqvlllvngaqlcggtlintiwvvsaahcfdkiknwrnliavlgehd
lsehdgdeqsrrvaqviipstyvpgttnhdiallrlhqpvvltdhvvplclpertfsert
lafvrfslvsgwgqlldrgatalelmvlnvprlmtqdclqqsrkvgdspniteymfcagy
sdgskdsckgdsggphathyrgtwyltgivswgqgcatvghfgvytrvsqyiewlqklmr
seprpgvllrapfp

Timeline for d2firh_:

• d2firh_ first appeared in SCOP 1.73, called d2firh1
  
• d2firh_ appears in SCOPe 2.06
  
• d2firh_ appears in the current release, SCOPe 2.08