SCOPe 2.04: Domain d2fhsa_: 2fhs A:

Lineage for d2fhsa_ (2fhs A:)

1. Root: SCOPe 2.04

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families)

5. Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (71 proteins)
   also known as short-chain dehydrogenases and SDR family
   parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7

6. Protein Enoyl-ACP reductase [51791] (11 species)

7. Species Escherichia coli [TaxId:562] [51794] (13 PDB entries)

8. Domain d2fhsa_: 2fhs A: [133501]
   Other proteins in same PDB: d2fhsc_
   automated match to d1qsgg_

Details for d2fhsa_

PDB Entry: 2fhs, 2.7 Å

PDB Description: Structure of Acyl Carrier Protein Bound to FabI, the Enoyl Reductase from Escherichia Coli

PDB Compounds: (A:) enoyl-[acyl-carrier-protein] reductase, NADH-dependent

SCOPe Domain Sequences for d2fhsa_:

Sequence; same for both SEQRES and ATOM records:

>d2fhsa_ c.2.1.2 (A:) Enoyl-ACP reductase {Escherichia coli [TaxId: 562]}
gflsgkrilvtgvasklsiaygiaqamhregaelaftyqndklkgrveefaaqlgsdivl
qcdvaedasidtmfaelgkvwpkfdgfvhsigfapgdqldgdyvnavtregfkiahdiss
ysfvamakacrsmlnpgsalltlsylgaeraipnynvmglakasleanvrymanamgpeg
vrvnaisagpirtlaasgikdfrkmlahceavtpirrtvtiedvgnsaaflcsdlsagis
gevvhvdggfsiaamnel

Timeline for d2fhsa_:

• d2fhsa_ first appeared in SCOP 1.73, called d2fhsa1
  
• d2fhsa_ appears in SCOPe 2.03
  
• d2fhsa_ appears in SCOPe 2.05
  
• d2fhsa_ appears in the current release, SCOPe 2.08