SCOP 1.75: Domain d2feta1: 2fet A:12-836

Lineage for d2feta1 (2fet A:12-836)

1. Root: SCOP 1.75

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.87: UDP-Glycosyltransferase/glycogen phosphorylase [53755] (1 superfamily)
   consists of two non-similar domains with 3 layers (a/b/a) each
   domain 1: parallel beta-sheet of 7 strands, order 3214567
   domain 2: parallel beta-sheet of 6 strands, order 321456

4. Superfamily c.87.1: UDP-Glycosyltransferase/glycogen phosphorylase [53756] (11 families)

5. Family c.87.1.4: Oligosaccharide phosphorylase [53766] (2 proteins)

6. Protein Glycogen phosphorylase [53767] (3 species)
   both domains are elaborated with many insertions

7. Species Rabbit (Oryctolagus cuniculus) [TaxId:9986] [53769] (103 PDB entries)
   Uniprot P00489
   Uniprot P00489
   Uniprot P00489 ! Uniprot P00489

8. Domain d2feta1: 2fet A:12-836 [133351]
   automatically matched to d1e1ya_
   complexed with h53, plp

Details for d2feta1

PDB Entry: 2fet, 2.03 Å

PDB Description: synthesis of c-d-glycopyranosyl-hydroquinones and-benzoquinones. inhibition of ptp1b. inhibition of and binding to glycogen phosphorylase in the crystal

PDB Compounds: (A:) Glycogen phosphorylase, muscle form

SCOP Domain Sequences for d2feta1:

Sequence, based on SEQRES records:

>d2feta1 c.87.1.4 (A:12-836) Glycogen phosphorylase {Rabbit (Oryctolagus cuniculus) [TaxId: 9986]}
qisvrglagvenvtelkknfnrhlhftlvkdrnvatprdyyfalahtvrdhlvgrwirtq
qhyyekdpkriyylslefymgrtlqntmvnlalenacdeatyqlgldmeeleeieedagl
gngglgrlaacfldsmatlglaaygygiryefgifnqkicggwqmeeaddwlrygnpwek
arpeftlpvhfygrvehtsqgakwvdtqvvlampydtpvpgyrnnvvntmrlwsakapnd
fnlkdfnvggyiqavldrnlaenisrvlypndnffegkelrlkqeyfvvaatlqdiirrf
ksskfgcrdpvrtnfdafpdkvaiqlndthpslaipelmrvlvdlerldwdkawevtvkt
caytnhtvlpealerwpvhlletllprhlqiiyeinqrflnrvaaafpgdvdrlrrmslv
eegavkrinmahlciagshavngvarihseilkktifkdfyelephkfqnktngitprrw
lvlcnpglaeiiaerigeeyisdldqlrkllsyvddeafirdvakvkqenklkfaayler
eykvhinpnslfdvqvkriheykrqllnclhvitlynrikkepnkfvvprtvmiggkaap
gyhmakmiiklitaigdvvnhdpvvgdrlrviflenyrvslaekvipaadlseqistagt
easgtgnmkfmlngaltigtmdganvemaeeageenffifgmrvedvdrldqrgynaqey
ydripelrqiieqlssgffspkqpdlfkdivnmlmhhdrfkvfadyeeyvkcqervsaly
knprewtrmvirniatsgkfssdrtiaqyareiwgvepsrqrlpa

Sequence, based on observed residues (ATOM records):

>d2feta1 c.87.1.4 (A:12-836) Glycogen phosphorylase {Rabbit (Oryctolagus cuniculus) [TaxId: 9986]}
qisvrglagvenvtelkknfnrhlhftlvkdrnvatprdyyfalahtvrdhlvgrwirtq
qhyyekdpkriyylslefymgrtlqntmvnlalenacdeatyqlgldmeeleeieedagl
gngglgrlaacfldsmatlglaaygygiryefgifnqkicggwqmeeaddwlrygnpwek
arpeftlpvhfygrvehtsqgakwvdtqvvlampydtpvpgyrnnvvntmrlwsakapnd
gyiqavldrnlaenisrvlypndnffegkelrlkqeyfvvaatlqdiirrfksstnfdaf
pdkvaiqlndthpslaipelmrvlvdlerldwdkawevtvktcaytnhtvlpealerwpv
hlletllprhlqiiyeinqrflnrvaaafpgdvdrlrrmslveegavkrinmahlciags
havngvarihseilkktifkdfyelephkfqnktngitprrwlvlcnpglaeiiaerige
eyisdldqlrkllsyvddeafirdvakvkqenklkfaaylereykvhinpnslfdvqvkr
iheykrqllnclhvitlynrikkepnkfvvprtvmiggkaapgyhmakmiiklitaigdv
vnhdpvvgdrlrviflenyrvslaekvipaadlseqistagteasgtgnmkfmlngalti
gtmdganvemaeeageenffifgmrvedvdrldqrgynaqeyydripelrqiieqlssgf
fspkqpdlfkdivnmlmhhdrfkvfadyeeyvkcqervsalyknprewtrmvirniatsg
kfssdrtiaqyareiwgvepsrqrlpa

Timeline for d2feta1:

• d2feta1 first appeared in SCOP 1.73
  
• d2feta1 is called d2feta_ in SCOPe 2.01
  
• d2feta1 appears in the current release, SCOPe 2.08, called d2feta_