SCOPe 2.04: Domain d2f9bh_: 2f9b H:

Lineage for d2f9bh_ (2f9b H:)

1. Root: SCOPe 2.04

2. Class b: All beta proteins [48724] (176 folds)

3. Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
   barrel, closed; n=6, S=8; greek-key
   duplication: consists of two domains of the same fold

4. Superfamily b.47.1: Trypsin-like serine proteases [50494] (5 families)

5. Family b.47.1.2: Eukaryotic proteases [50514] (48 proteins)

6. Protein Coagulation factor VIIa [50550] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [50551] (39 PDB entries)
   Uniprot P08709 213-466 ! Uniprot P08709 213-446

8. Domain d2f9bh_: 2f9b H: [133155]
   Other proteins in same PDB: d2f9bl1, d2f9bl2, d2f9bt1, d2f9bt2
   automated match to d1cvwh_
   complexed with n1h

Details for d2f9bh_

PDB Entry: 2f9b, 2.54 Å

PDB Description: discovery of novel heterocyclic factor viia inhibitors

PDB Compounds: (H:) Coagulation factor VII

SCOPe Domain Sequences for d2f9bh_:

Sequence; same for both SEQRES and ATOM records:

>d2f9bh_ b.47.1.2 (H:) Coagulation factor VIIa {Human (Homo sapiens) [TaxId: 9606]}
ivggkvcpkgecpwqvlllvngaqlcggtlintiwvvsaahcfdkiknwrnliavlgehd
lsehdgdeqsrrvaqviipstyvpgttnhdiallrlhqpvvltdhvvplclpertfsert
lafvrfslvsgwgqlldrgatalelmvlnvprlmtqdclqqsrkvgdspniteymfcagy
sdgskdsckgdsggphathyrgtwyltgivswgqgcatvghfgvytrvsqyiewlqklmr
seprpgvllrapfp

Timeline for d2f9bh_:

• d2f9bh_ first appeared in SCOP 1.73, called d2f9bh1
  
• d2f9bh_ appears in SCOPe 2.03
  
• d2f9bh_ appears in SCOPe 2.05
  
• d2f9bh_ appears in the current release, SCOPe 2.08