SCOPe 2.05: Domain d2f8sa2: 2f8s A:315-706

Lineage for d2f8sa2 (2f8s A:315-706)

1. Root: SCOPe 2.05

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.55: Ribonuclease H-like motif [53066] (7 superfamilies)
   3 layers: a/b/a; mixed beta-sheet of 5 strands, order 32145; strand 2 is antiparallel to the rest

4. Superfamily c.55.3: Ribonuclease H-like [53098] (15 families)
   consists of one domain of this fold

5. Family c.55.3.10: PIWI domain [110640] (4 proteins)
   Pfam PF02171

6. Protein automated matches [254529] (1 species)
   not a true protein
7. Species Aquifex aeolicus [TaxId:63363] [255167] (2 PDB entries)

8. Domain d2f8sa2: 2f8s A:315-706 [133141]
   Other proteins in same PDB: d2f8sa1, d2f8sb1
   automated match to d1yvua2
   protein/RNA complex

Details for d2f8sa2

PDB Entry: 2f8s, 3 Å

PDB Description: Crystal structure of Aa-Ago with externally-bound siRNA

PDB Compounds: (A:) Argonaute protein

SCOPe Domain Sequences for d2f8sa2:

Sequence; same for both SEQRES and ATOM records:

>d2f8sa2 c.55.3.10 (A:315-706) automated matches {Aquifex aeolicus [TaxId: 63363]}
klnfkdtvldakgkntkvitnlrkflelcrpfvkkdvlsveiisvsvykklewrkeeflk
elinflknkgiklkikgkslilaqtreeakeklipvinkikdvdlvivfleeypkvdpyk
sfllydfvkrellkkmipsqvilnrtlknenlkfvllnvaeqvlaktgnipyklkeiegk
vdafvgidisritrdgktvnavaftkifnskgelvryyltsypafgekltekaigdvfsl
leklgfkkgskivvhrdgrlyrdevaafkkygelygyslelleiikrnnprffsnekfik
gyfyklsedsvilatynqvyegthqpikvrkvygelpvevlcsqilsltlmnyssfqpik
lpatvhysdkitklmlrgiepikkegdimywl

Timeline for d2f8sa2:

• d2f8sa2 first appeared in SCOP 1.73
  
• d2f8sa2 appears in SCOPe 2.04
  
• d2f8sa2 does not appear in SCOPe 2.06