Lineage for d2f8sa2 (2f8s A:315-706)

  1. Root: SCOPe 2.01
  2. 968085Class c: Alpha and beta proteins (a/b) [51349] (147 folds)
  3. 995076Fold c.55: Ribonuclease H-like motif [53066] (7 superfamilies)
    3 layers: a/b/a; mixed beta-sheet of 5 strands, order 32145; strand 2 is antiparallel to the rest
  4. 995888Superfamily c.55.3: Ribonuclease H-like [53098] (15 families) (S)
    consists of one domain of this fold
  5. 996500Family c.55.3.10: PIWI domain [110640] (3 proteins)
    Pfam PF02171
  6. 996501Protein Argonaute homologue Aq_1447 [142501] (1 species)
    includes the middle domain
  7. 996502Species Aquifex aeolicus [TaxId:63363] [142502] (4 PDB entries)
    Uniprot O67434 315-706
  8. 996504Domain d2f8sa2: 2f8s A:315-706 [133141]
    Other proteins in same PDB: d2f8sa1, d2f8sb1
    automatically matched to 1YVU A:315-706
    protein/RNA complex

Details for d2f8sa2

PDB Entry: 2f8s (more details), 3 Å

PDB Description: Crystal structure of Aa-Ago with externally-bound siRNA
PDB Compounds: (A:) Argonaute protein

SCOPe Domain Sequences for d2f8sa2:

Sequence; same for both SEQRES and ATOM records: (download)

>d2f8sa2 c.55.3.10 (A:315-706) Argonaute homologue Aq_1447 {Aquifex aeolicus [TaxId: 63363]}
klnfkdtvldakgkntkvitnlrkflelcrpfvkkdvlsveiisvsvykklewrkeeflk
elinflknkgiklkikgkslilaqtreeakeklipvinkikdvdlvivfleeypkvdpyk
sfllydfvkrellkkmipsqvilnrtlknenlkfvllnvaeqvlaktgnipyklkeiegk
vdafvgidisritrdgktvnavaftkifnskgelvryyltsypafgekltekaigdvfsl
leklgfkkgskivvhrdgrlyrdevaafkkygelygyslelleiikrnnprffsnekfik
gyfyklsedsvilatynqvyegthqpikvrkvygelpvevlcsqilsltlmnyssfqpik
lpatvhysdkitklmlrgiepikkegdimywl

SCOPe Domain Coordinates for d2f8sa2:

Click to download the PDB-style file with coordinates for d2f8sa2.
(The format of our PDB-style files is described here.)

Timeline for d2f8sa2:

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Domains from same chain:
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d2f8sa1