SCOPe 2.03: Domain d2f8sa1: 2f8s A:4-314

Lineage for d2f8sa1 (2f8s A:4-314)

1. Root: SCOPe 2.03

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.34: SH3-like barrel [50036] (21 superfamilies)
   barrel, partly opened; n*=4, S*=8; meander
   the last strand is interrupted by a turn of 3-10 helix

4. Superfamily b.34.14: PAZ domain [101690] (1 family)

5. Family b.34.14.1: PAZ domain [101691] (6 proteins)

6. Protein Argonaute homologue Aq_1447 [141227] (1 species)
   includes the N-terminal domain

7. Species Aquifex aeolicus [TaxId:63363] [141228] (4 PDB entries)
   Uniprot O67434 4-314

8. Domain d2f8sa1: 2f8s A:4-314 [133140]
   Other proteins in same PDB: d2f8sa2, d2f8sb2
   automatically matched to 1YVU A:4-314
   protein/RNA complex

Details for d2f8sa1

PDB Entry: 2f8s, 3 Å

PDB Description: Crystal structure of Aa-Ago with externally-bound siRNA

PDB Compounds: (A:) Argonaute protein

SCOPe Domain Sequences for d2f8sa1:

Sequence; same for both SEQRES and ATOM records:

>d2f8sa1 b.34.14.1 (A:4-314) Argonaute homologue Aq_1447 {Aquifex aeolicus [TaxId: 63363]}
eallnlyrieyrpkdttftvfkptheiqkeklnkvrwrvflqtglptfrredefwcagkv
ekdtlyltlsngeivelkrvgeeefrgfqnerecqelfrdfltktkvkdkfisdfykkfr
dkitvqgknrkialipevnekvlkseegyfllhldlkfriqpfetlqtllerndfnpkri
rvkpigidfvgrvqdvfkakekgeeffrlcmersthksskkaweellknrelrekaflvv
lekgytypatilkpvltyenledeernevadivrmepgkrlnliryilrryvkalrdygw
yispeeerakg

Timeline for d2f8sa1:

• d2f8sa1 first appeared in SCOP 1.73
  
• d2f8sa1 appears in SCOPe 2.02
  
• d2f8sa1 appears in SCOPe 2.04
  
• d2f8sa1 appears in the current release, SCOPe 2.08