Lineage for d2f81b_ (2f81 B:)

  1. Root: SCOPe 2.02
  2. 1103260Class b: All beta proteins [48724] (174 folds)
  3. 1130027Fold b.50: Acid proteases [50629] (1 superfamily)
    barrel, closed; n=6, S=10, complex topology
  4. 1130028Superfamily b.50.1: Acid proteases [50630] (4 families) (S)
  5. 1130029Family b.50.1.1: Retroviral protease (retropepsin) [50631] (9 proteins)
    dimer of identical mono-domain chains, each containing (6,10) barrel
  6. 1130045Protein Human immunodeficiency virus type 1 protease [50632] (7 species)
  7. 1130131Species Human immunodeficiency virus type 1 [TaxId:11676] [50633] (413 PDB entries)
    Uniprot P35963 57-155 ! Uniprot P04587 69-167 ! Uniprot P03366 69-167 ! Uniprot P03367 69-167 ! Uniprot P03368 69-167
  8. 1130212Domain d2f81b_: 2f81 B: [133117]
    automated match to d1dw6c_
    complexed with 017, cl, gol, na; mutant

Details for d2f81b_

PDB Entry: 2f81 (more details), 1.25 Å

PDB Description: hiv-1 protease mutant l90m complexed with inhibitor tmc114
PDB Compounds: (B:) Pol polyprotein

SCOPe Domain Sequences for d2f81b_:

Sequence; same for both SEQRES and ATOM records: (download)

>d2f81b_ b.50.1.1 (B:) Human immunodeficiency virus type 1 protease {Human immunodeficiency virus type 1 [TaxId: 11676]}
pqitlwkrplvtikiggqlkealldtgaddtvieemslpgrwkpkmiggiggfikvrqyd
qiiieiaghkaigtvlvgptpvniigrnlmtqigatlnf

SCOPe Domain Coordinates for d2f81b_:

Click to download the PDB-style file with coordinates for d2f81b_.
(The format of our PDB-style files is described here.)

Timeline for d2f81b_: