SCOPe 2.06: Domain d2f7sb_: 2f7s B:

Lineage for d2f7sb_ (2f7s B:)

1. Root: SCOPe 2.06

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (26 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.8: G proteins [52592] (79 proteins)
   core: mixed beta-sheet of 6 strands, order 231456; strand 2 is antiparallel to the rest

6. Protein Rab27b [142263] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [142264] (1 PDB entry)
   Uniprot O00194 4-189

8. Domain d2f7sb_: 2f7s B: [133105]
   automated match to d2f7sa1
   complexed with gdp, mg

Details for d2f7sb_

PDB Entry: 2f7s, 2.7 Å

PDB Description: The crystal structure of human Rab27b bound to GDP

PDB Compounds: (B:) Ras-related protein Rab-27B

SCOPe Domain Sequences for d2f7sb_:

Sequence, based on SEQRES records:

>d2f7sb_ c.37.1.8 (B:) Rab27b {Human (Homo sapiens) [TaxId: 9606]}
ydylikllalgdsgvgkttflyrytdnkfnpkfittvgidfrekrvvynaqgpngssgka
fkvhlqlwdtagqerfrslttaffrdamgfllmfdltsqqsflnvrnwmsqlqanaycen
pdivlignkadlpdqrevnerqareladkygipyfetsaatgqnvekavetlldlimkrm
eqcv

Sequence, based on observed residues (ATOM records):

>d2f7sb_ c.37.1.8 (B:) Rab27b {Human (Homo sapiens) [TaxId: 9606]}
ydylikllalgdsgvgkttflyrytdnkfnpkfittvgidfrekrvvynakafkvhlqlw
dtagqerfrslttaffrdamgfllmfdltsqqsflnvrnwmsqlqanaycenpdivlign
kadlpdqrevnerqareladkygipyfetsaatgqnvekavetlldlimkrmeqcv

Timeline for d2f7sb_:

• d2f7sb_ first appeared in SCOP 1.73, called d2f7sb1
  
• d2f7sb_ appears in SCOPe 2.05
  
• d2f7sb_ appears in SCOPe 2.07
  
• d2f7sb_ appears in the current release, SCOPe 2.08