SCOPe 2.01: Domain d2f66d_: 2f66 D:

Lineage for d2f66d_ (2f66 D:)

1. Root: SCOPe 2.01

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.2: Long alpha-hairpin [46556] (20 superfamilies)
   2 helices; antiparallel hairpin, left-handed twist

4. Superfamily a.2.17: Endosomal sorting complex assembly domain [140111] (3 families)
   forms 'fan'-like heterooligomers, in which the domains of different subunit make similar interactions at the tip of the hairpin

5. Family a.2.17.1: VPS23 C-terminal domain [140112] (1 protein)

6. Protein Vacuolar protein sorting-associated protein 23, VPS23 [140113] (1 species)

7. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [140114] (3 PDB entries)
   Uniprot P25604 322-385! Uniprot P25604 325-383

8. Domain d2f66d_: 2f66 D: [133030]
   Other proteins in same PDB: d2f66b1, d2f66c1, d2f66e_, d2f66f_
   automated match to d2f66a1
   complexed with so4

Details for d2f66d_

PDB Entry: 2f66, 2.8 Å

PDB Description: structure of the escrt-i endosomal trafficking complex

PDB Compounds: (D:) suppressor protein stp22 of temperature-sensitive alpha-factor receptor and arginine permease

SCOPe Domain Sequences for d2f66d_:

Sequence; same for both SEQRES and ATOM records:

>d2f66d_ a.2.17.1 (D:) Vacuolar protein sorting-associated protein 23, VPS23 {Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
mtdglnqlynlvaqdyaltdtiealsrmlhrgtipldtfvkqgrelarqqflvrwhiqri
tspls

Timeline for d2f66d_:

• d2f66d_ first appeared in SCOP 1.73, called d2f66d1
  
• d2f66d_ was called d2f66d1 in SCOP 1.75
  
• d2f66d_ appears in SCOPe 2.02
  
• d2f66d_ appears in the current release, SCOPe 2.08, called d2f66d2