SCOPe 2.08: Domain d2f54g2: 2f54 G:1-99

Lineage for d2f54g2 (2f54 G:1-99)

1. Root: SCOPe 2.08

2. Class b: All beta proteins [48724] (180 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (5 families)

5. Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (24 proteins)

6. Protein beta2-microglobulin [88600] (7 species)

7. Species Human (Homo sapiens) [TaxId:9606] [88602] (480 PDB entries)
   Uniprot P61769 21-119 ! Uniprot P01884

8. Domain d2f54g2: 2f54 G:1-99 [132973]
   Other proteins in same PDB: d2f54a1, d2f54a2, d2f54b3, d2f54d1, d2f54d2, d2f54e1, d2f54e2, d2f54f1, d2f54f2, d2f54g3, d2f54k1, d2f54k2, d2f54l1, d2f54l2
   automated match to d1ao7b_

Details for d2f54g2

PDB Entry: 2f54, 2.7 Å

PDB Description: directed evolution of human t cell receptor cdr2 residues by phage display dramatically enhances affinity for cognate peptide-mhc without increasing apparent cross-reactivity

PDB Compounds: (G:) Beta-2-microglobulin

SCOPe Domain Sequences for d2f54g2:

Sequence; same for both SEQRES and ATOM records:

>d2f54g2 b.1.1.2 (G:1-99) beta2-microglobulin {Human (Homo sapiens) [TaxId: 9606]}
iqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskdw
sfyllycteftptekdeyacrvnhvtlsqpcivkwdrdm

Timeline for d2f54g2:

• d2f54g2 first appeared in SCOP 1.73, called d2f54g1
  
• d2f54g2 appears in SCOPe 2.07