SCOP 1.75: Domain d2f0yb1: 2f0y B:21-421

Lineage for d2f0yb1 (2f0y B:21-421)

1. Root: SCOP 1.75

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.102: alpha/alpha toroid [48207] (6 superfamilies)
   multihelical; up to seven alpha-hairpins are arranged in closed circular array; there may be sequence similarities between different superfamilies

4. Superfamily a.102.4: Terpenoid cyclases/Protein prenyltransferases [48239] (4 families)

5. Family a.102.4.3: Protein prenyltransferases [48246] (2 proteins)

6. Protein Protein farnesyltransferase, beta-subunit [48247] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [69090] (19 PDB entries)
   Uniprot P49356

8. Domain d2f0yb1: 2f0y B:21-421 [132682]
   Other proteins in same PDB: d2f0ya1
   automatically matched to d1jcqb_
   complexed with 3mn, fpp, zn

Details for d2f0yb1

PDB Entry: 2f0y, 2.7 Å

PDB Description: Crystal Structure Of Human Protein Farnesyltransferase Complexed With Farnesyl Diphosphate and hydantoin derivative

PDB Compounds: (B:) Protein farnesyltransferase beta subunit

SCOP Domain Sequences for d2f0yb1:

Sequence, based on SEQRES records:

>d2f0yb1 a.102.4.3 (B:21-421) Protein farnesyltransferase, beta-subunit {Human (Homo sapiens) [TaxId: 9606]}
eplyslrpeharerlqddsvetvtsieqakveekiqevfssykfnhlvprlvlqrekhfh
ylkrglrqltdayecldasrpwlcywilhslelldepipqivatdvcqflelcqspeggf
gggpgqyphlaptyaavnalciigteeaydiinrekllqylyslkqpdgsflmhvggevd
vrsaycaasvasltniitpdlfegtaewiarcqnweggiggvpgmeahggytfcglaalv
ilkrerslnlksllqwvtsrqmrfeggfqgrcnklvdgcysfwqagllpllhralhaqgd
palsmshwmfhqqalqeyilmccqcpagglldkpgksrdfyhtcyclsglsiaqhfgsga
mlhdvvlgvpenalqpthpvynigpdkviqattyflqkpvp

Sequence, based on observed residues (ATOM records):

>d2f0yb1 a.102.4.3 (B:21-421) Protein farnesyltransferase, beta-subunit {Human (Homo sapiens) [TaxId: 9606]}
eplyslrpeharerlqddsvetvtsieqakveekiqevfssykrlvlqrekhfhylkrgl
rqltdayecldasrpwlcywilhslelldepipqivatdvcqflelcqspeggfgggpgq
yphlaptyaavnalciigteeaydiinrekllqylyslkqpdgsflmhvggevdvrsayc
aasvasltniitpdlfegtaewiarcqnweggiggvpgmeahggytfcglaalvilkrer
slnlksllqwvtsrqmrfeggfqgrcnklvdgcysfwqagllpllhralhaqgdpalsms
hwmfhqqalqeyilmccqcpagglldkpgksrdfyhtcyclsglsiaqhfgsgamlhdvv
lgvpenalqpthpvynigpdkviqattyflqkpvp

Timeline for d2f0yb1:

• d2f0yb1 first appeared in SCOP 1.73
  
• d2f0yb1 appears in SCOPe 2.01
  
• d2f0yb1 appears in the current release, SCOPe 2.08, called d2f0yb_