Class c: Alpha and beta proteins (a/b) [51349] (147 folds) |
Fold c.36: Thiamin diphosphate-binding fold (THDP-binding) [52517] (1 superfamily) 3 layers: a/b/a; parallel beta-sheet of 6 strands, order 213465 |
Superfamily c.36.1: Thiamin diphosphate-binding fold (THDP-binding) [52518] (8 families) there are two different functional modules of this fold: pyridine-binding (Pyr) and pyrophosphate-binding (PP) modules two Pyr and two PP modules assemble together in a conserved heterotetrameric core that binds two THDP coenzyme molecules |
Family c.36.1.9: Pyruvate oxidase and decarboxylase PP module [88749] (8 proteins) the N-terminal, Pyr module is separated from the C-terminal, PP module by an alpa/beta domain of Rossmann-like topology |
Protein Pyruvate oxidase [88754] (2 species) |
Species Lactobacillus plantarum [TaxId:1590] [88755] (7 PDB entries) |
Domain d2ez8a3: 2ez8 A:366-593 [132623] Other proteins in same PDB: d2ez8a1, d2ez8a2, d2ez8b1, d2ez8b2 automatically matched to d1powa3 complexed with fad, mg, na, pyr, tdl; mutant |
PDB Entry: 2ez8 (more details), 1.96 Å
SCOP Domain Sequences for d2ez8a3:
Sequence; same for both SEQRES and ATOM records: (download)
>d2ez8a3 c.36.1.9 (A:366-593) Pyruvate oxidase {Lactobacillus plantarum [TaxId: 1590]} kqegplqayqvlravnkiaepdaiysidvgdinlnanrhlkltpsnrhitsnlfatmgvg ipgaiaaklnyperqvfnlagdggasmtmqdlatqvqyhlpvinvvftncqygwikdeqe dtnqndfigvefndidfskiadgvhmqafrvnkieqlpdvfeqakaiaqhepvlidavit gdrplpaeklrldsamssaadieafkqryeaqdlqplstylkqfgldd
Timeline for d2ez8a3: