SCOPe 2.08: Domain d2exlb_: 2exl B:

Lineage for d2exlb_ (2exl B:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.122: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase [55873] (1 superfamily)
   8-stranded mixed beta-sheet; 2 layers: alpha/beta

4. Superfamily d.122.1: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase [55874] (5 families)

5. Family d.122.1.1: Heat shock protein 90, HSP90, N-terminal domain [55875] (2 proteins)

6. Protein HSP90 [55876] (3 species)

7. Species Dog (Canis familiaris) [TaxId:9615] [103225] (33 PDB entries)
   Uniprot P41148 76-285; Endoplasmin, GRP94

8. Domain d2exlb_: 2exl B: [132560]
   automated match to d1u2oa_
   complexed with 1pe, gdm, pg4

Details for d2exlb_

PDB Entry: 2exl, 2.35 Å

PDB Description: grp94 n-terminal domain bound to geldanamycin

PDB Compounds: (B:) Endoplasmin

SCOPe Domain Sequences for d2exlb_:

Sequence, based on SEQRES records:

>d2exlb_ d.122.1.1 (B:) HSP90 {Dog (Canis familiaris) [TaxId: 9615]}
sekfafqaevnrmmkliinslyknkeiflrelisnasdaldkirlisltdenalagneel
tvkikcdkeknllhvtdtgvgmtreelvknlgtiaksgtseflnkmteaqedgqstseli
gqfgvgfysaflvadkvivtskhnndtqhiwesdsnefsviadprgntlgrgttitlvlk
eeasdyleldtiknlvkkysqfinfpiyvwssktggggktvwdwelmn

Sequence, based on observed residues (ATOM records):

>d2exlb_ d.122.1.1 (B:) HSP90 {Dog (Canis familiaris) [TaxId: 9615]}
sekfafqaevnrmmkliinslyknkeiflrelisnasdaldkirlisltdenalagneel
tvkikcdkeknllhvtdtgvgmtreelvknlgtistseligqfgvgfysaflvadkvivt
skhnndtqhiwesdsnefsviadprgntlgrgttitlvlkeeasdyleldtiknlvkkys
qfinfpiyvwssktktvwdwelmn

Timeline for d2exlb_:

• d2exlb_ first appeared in SCOP 1.73, called d2exlb1
  
• d2exlb_ appears in SCOPe 2.07