SCOP 1.75: Domain d2exaa1: 2exa A:26-477

Lineage for d2exaa1 (2exa A:26-477)

1. Root: SCOP 1.75

2. Class e: Multi-domain proteins (alpha and beta) [56572] (66 folds)

3. Fold e.3: beta-lactamase/transpeptidase-like [56600] (1 superfamily)
   contains a cluster of helices and an alpha+beta sandwich

4. Superfamily e.3.1: beta-lactamase/transpeptidase-like [56601] (3 families)

5. Family e.3.1.3: Dac-like [144040] (3 proteins)
   Pfam PF02113; D-Ala-D-Ala carboxypeptidase 3 (S13) family; contains a large insertion comprising two subdomains: (d1) aplha+beta with topological similarity to one subunit of the DTD-like family ((69501)) and (d2) six-stranded beta-sandwich with a crossed-loop topology

6. Protein DD-carboxypeptidase DacB [144045] (1 species)
   Penicillin-binding protein 4

7. Species Escherichia coli [TaxId:562] [144046] (6 PDB entries)
   Uniprot P24228 22-477

8. Domain d2exaa1: 2exa A:26-477 [132521]
   automatically matched to 2EX2 A:22-477
   complexed with fro, gol

Details for d2exaa1

PDB Entry: 2exa, 1.7 Å

PDB Description: crystal structure of penicillin binding protein 4 (dacb) from escherichia coli, complexed with farom

PDB Compounds: (A:) Penicillin-binding protein 4

SCOP Domain Sequences for d2exaa1:

Sequence, based on SEQRES records:

>d2exaa1 e.3.1.3 (A:26-477) DD-carboxypeptidase DacB {Escherichia coli [TaxId: 562]}
yitqlpaganlalmvqkvgasapaidyhsqqmalpastqkvitalaaliqlgpdfrfttt
letkgnvengvlkgdlvarfgadptlkrqdirnmvatlkksgvnqidgnvlidtsifash
dkapgwpwndmtqcfsappaaaivdrncfsvslysapkpgdmafirvasyypvtmfsqvr
tlprgsaeaqyceldvvpgdlnrftltgclpqrseplplafavqdgasyagailkyelkq
agitwsgtllrqtqvnepgtvvaskqsaplhdllkimlkksdnmiadtvfrmigharfnv
pgtwragsdavrqilrqqagvdigntiiadgsglsrhnliapatmmqvlqyiaqhdneln
fismlplagydgslqyraglhqagvdgkvsaktgslqgvynlagfittasgqrmafvqyl
sgyavepadqrnrriplvrfesrlykdiyqnn

Sequence, based on observed residues (ATOM records):

>d2exaa1 e.3.1.3 (A:26-477) DD-carboxypeptidase DacB {Escherichia coli [TaxId: 562]}
yitqlpaganlalmvqkvgasapaidyhsqqmalpastqkvitalaaliqlgpdfrfttt
letkgnvengvlkgdlvarfgadptlkrqdirnmvatlkksgvnqidgnvlidtsifash
dkapgwpwndmtqcfsappaaaivdrncfsvslysapkpgdmafirvasyypvtmfsqvr
tlprgsaeaqyceldvvpgdlnrftltgclpqrseplplafavqdgasyagailkyelkq
agitwsgtllrqtqvnepgtvvaskqsaplhdllkimlkksdnmiadtvfrmigharfnv
pgtwragsdavrqilrqqagvdigntiiadgsglsrhnliapatmmqvlqyiaqhdneln
fismlplagydgslqyraglhqagvdgkvsaktgslqgvynlagfittasgqrmafvqyl
sgyariplvrfesrlykdiyqnn

Timeline for d2exaa1:

• d2exaa1 first appeared in SCOP 1.73
  
• d2exaa1 is called d2exaa_ in SCOPe 2.01
  
• d2exaa1 appears in the current release, SCOPe 2.08, called d2exaa_