SCOPe 2.01: Domain d2ewpd_: 2ewp D:

Lineage for d2ewpd_ (2ewp D:)

1. Root: SCOPe 2.01

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Orphan nuclear receptor ERR3 [81916] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [81917] (13 PDB entries)
   Uniprot O75454 233-458

8. Domain d2ewpd_: 2ewp D: [132491]
   automated match to d1tfca_
   complexed with txf

Details for d2ewpd_

PDB Entry: 2ewp, 2.3 Å

PDB Description: crystal structure of estrogen related receptor-3 (err-gamma) ligand binding domaind with tamoxifen analog gsk5182

PDB Compounds: (D:) Estrogen-related receptor gamma

SCOPe Domain Sequences for d2ewpd_:

Sequence; same for both SEQRES and ATOM records:

>d2ewpd_ a.123.1.1 (D:) Orphan nuclear receptor ERR3 {Human (Homo sapiens) [TaxId: 9606]}
nkivshllvaepekiyampdptvpdsdikalttlcdladrelvviigwakhipgfstlsl
adqmsllqsawmeililgvvyrslsfedelvyaddyimdedqsklaglldlnnailqlvk
kyksmklekeefvtlkaialansdsmhiedveavqklqdvlhealqdyeagqhmedprra
gkmlmtlpllrqtstkavqhfyniklegkvpmhklflemle

Timeline for d2ewpd_:

• d2ewpd_ first appeared in SCOP 1.73, called d2ewpd1
  
• d2ewpd_ was called d2ewpd1 in SCOP 1.75
  
• d2ewpd_ appears in SCOPe 2.02
  
• d2ewpd_ appears in the current release, SCOPe 2.08