Lineage for d2ewaa_ (2ewa A:)

  1. Root: SCOPe 2.06
  2. 2170735Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
  3. 2218047Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2218048Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2218179Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 2220075Protein MAP kinase p38 [56129] (2 species)
    CMGC group; ERK/MAPK subfamily; serine/threonine kinase
  7. 2220279Species Mouse (Mus musculus) [TaxId:10090] [56131] (25 PDB entries)
  8. 2220289Domain d2ewaa_: 2ewa A: [132451]
    automated match to d1a9ua_
    complexed with sb2

Details for d2ewaa_

PDB Entry: 2ewa (more details), 2.1 Å

PDB Description: Dual binding mode of pyridinylimidazole to MAP kinase p38
PDB Compounds: (A:) Mitogen-activated protein kinase 14

SCOPe Domain Sequences for d2ewaa_:

Sequence, based on SEQRES records: (download)

>d2ewaa_ d.144.1.7 (A:) MAP kinase p38 {Mouse (Mus musculus) [TaxId: 10090]}
rptfyrqelnktiwevperyqnlspvgsgaygsvcaafdtktglrvavkklsrpfqsiih
akrtyrelrllkhmkhenviglldvftparsleefndvylvthlmgadlnnivkcqkltd
dhvqfliyqilrglkyihsadiihrdlkpsnlavnedcelkildfglarhtddemtgyva
trwyrapeimlnwmhynqtvdiwsvgcimaelltgrtlfpgtdhidqlklilrlvgtpga
ellkkissesarnyiqsltqmpkmnfanvfiganplavdllekmlvldsdkritaaqala
hayfaqyhdpddepvadpydqsfesrdllidewksltydevisfvpppld

Sequence, based on observed residues (ATOM records): (download)

>d2ewaa_ d.144.1.7 (A:) MAP kinase p38 {Mouse (Mus musculus) [TaxId: 10090]}
rptfyrqelnktiwevperyqnlspvgsgaygsvcaafdtktglrvavkklsrpfqsiih
akrtyrelrllkhmkhenviglldvftparsleefndvylvthlmgadlnniltddhvqf
liyqilrglkyihsadiihrdlkpsnlavnedcelkildfgtrwyrapeimlnmhynqtv
diwsvgcimaelltgrtlfpgtdhidqlklilrlvgtpgaellkkissesarnyiqsltq
mpkmnfanvfiganplavdllekmlvldsdkritaaqalahayfaqyhdpddepvadpyd
qsfesrdllidewksltydevisfvpppld

SCOPe Domain Coordinates for d2ewaa_:

Click to download the PDB-style file with coordinates for d2ewaa_.
(The format of our PDB-style files is described here.)

Timeline for d2ewaa_: