Lineage for d2etmb1 (2etm B:415-686)

  1. Root: SCOP 1.75
  2. 849709Class d: Alpha and beta proteins (a+b) [53931] (376 folds)
  3. 874255Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 874256Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (7 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 874317Family d.144.1.7: Protein kinases, catalytic subunit [88854] (63 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 874817Protein Focal adhesion kinase 1 (fak) [103292] (1 species)
    PTK group; FAK subfamily; non-membrane spanning protein tyrosine kinase
  7. 874818Species Human (Homo sapiens) [TaxId:9606] [103293] (4 PDB entries)
  8. 874824Domain d2etmb1: 2etm B:415-686 [132364]
    automatically matched to d1mp8a_
    complexed with 7py

Details for d2etmb1

PDB Entry: 2etm (more details), 2.3 Å

PDB Description: Crystal Structure of Focal Adhesion Kinase Domain Complexed with 7H-Pyrrolo [2,3-d] pyrimidine Derivative
PDB Compounds: (B:) Focal adhesion kinase 1

SCOP Domain Sequences for d2etmb1:

Sequence, based on SEQRES records: (download)

>d2etmb1 d.144.1.7 (B:415-686) Focal adhesion kinase 1 (fak) {Human (Homo sapiens) [TaxId: 9606]}
yeiqrerielgrcigegqfgdvhqgiymspenpalavaiktcknctsdsvrekflqealt
mrqfdhphivkligvitenpvwiimelctlgelrsflqvrkysldlaslilyayqlstal
ayleskrfvhrdiaarnvlvssndcvklgdfglsrymedstyykaskgklpikwmapesi
nfrrftsasdvwmfgvcmweilmhgvkpfqgvknndvigriengerlpmppncpptlysl
mtkcwaydpsrrprftelkaqlstileeekaq

Sequence, based on observed residues (ATOM records): (download)

>d2etmb1 d.144.1.7 (B:415-686) Focal adhesion kinase 1 (fak) {Human (Homo sapiens) [TaxId: 9606]}
yeiqrerielgrcigegqfgdvhqgiymspenpalavaiktcknctsdsvrekflqealt
mrqfdhphivkligvitenpvwiimelctlgelrsflqvrkysldlaslilyayqlstal
ayleskrfvhrdiaarnvlvssndcvklgdfglsrlpikwmapesinfrrftsasdvwmf
gvcmweilmhgvkpfqgvknndvigriengerlpmppncpptlyslmtkcwaydpsrrpr
ftelkaqlstileeekaq

SCOP Domain Coordinates for d2etmb1:

Click to download the PDB-style file with coordinates for d2etmb1.
(The format of our PDB-style files is described here.)

Timeline for d2etmb1: