SCOPe 2.08: Domain d2e2ia1: 2e2i A:3-1449

Lineage for d2e2ia1 (2e2i A:3-1449)

1. Root: SCOPe 2.08

2. Class e: Multi-domain proteins (alpha and beta) [56572] (74 folds)

3. Fold e.29: beta and beta-prime subunits of DNA dependent RNA-polymerase [64483] (1 superfamily)
   Multidomain subunits of complex domain organization

4. Superfamily e.29.1: beta and beta-prime subunits of DNA dependent RNA-polymerase [64484] (3 families)
   The catalytic site is formed by the association of two double-psi beta-barrel domains, one from each subunit

5. Family e.29.1.2: RNA-polymerase beta-prime [64490] (4 proteins)

6. Protein RBP1 [64486] (2 species)

7. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [64487] (24 PDB entries)
   Uniprot P04050; part of multichain biological unit

8. Domain d2e2ia1: 2e2i A:3-1449 [131994]
   Other proteins in same PDB: d2e2ib1, d2e2ic1, d2e2ic2, d2e2ie1, d2e2ie2, d2e2if1, d2e2ih1, d2e2ii1, d2e2ii2, d2e2ij1, d2e2ik1, d2e2il1
   automatically matched to d1i50a_
   protein/DNA complex; protein/RNA complex; complexed with dgt, mg, zn

Details for d2e2ia1

PDB Entry: 2e2i, 3.41 Å

PDB Description: RNA polymerase II elongation complex in 5 mM Mg+2 with 2'-dGTP

PDB Compounds: (A:) DNA-directed RNA polymerase II largest subunit

SCOPe Domain Sequences for d2e2ia1:

Sequence, based on SEQRES records:

>d2e2ia1 e.29.1.2 (A:3-1449) RBP1 {Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
gqqyssaplrtvkevqfglfspeevraisvakirfpetmdetqtrakigglndprlgsid
rnlkcqtcqegmnecpghfghidlakpvfhvgfiakikkvcecvcmhcgkllldehnelm
rqalaikdskkrfaaiwtlcktkmvcetdvpseddptqlvsrggcgntqptirkdglklv
gswkkdratgdadepelrvlsteeilnifkhisvkdftslgfnevfsrpewmiltclpvp
pppvrpsisfnesqrgeddltfkladilkanisletlehngaphhaieeaesllqfhvat
ymdndiagqpqalqksgrpvksirarlkgkegrirgnlmgkrvdfsartvisgdpnleld
qvgvpksiaktltypevvtpynidrltqlvrngpnehpgakyvirdsgdridlryskrag
diqlqygwkverhimdndpvlfnrqpslhkmsmmahrvkvipystfrlnlsvtspynadf
dgdemnlhvpqseetraelsqlcavplqivspqsnkpcmgivqdtlcgirkltlrdtfie
ldqvlnmlywvpdwdgviptpaiikpkplwsgkqilsvaipngihlqrfdegttllspkd
ngmliidgqiifgvvekktvgssngglihvvtrekgpqvcaklfgniqkvvnfwllhngf
stgigdtiadgptmreitetiaeakkkvldvtkeaqanlltakhgmtlresfednvvrfl
neardkagrlaevnlkdlnnvkqmvmagskgsfiniaqmsacvgqqsvegkriafgfvdr
tlphfskddyspeskgfvensylrgltpqefffhamggreglidtavktaetgyiqrrlv
kaledimvhydnttrnslgnviqfiygedgmdaahiekqsldtiggsdaafekryrvdll
ntdhtldpsllesgseilgdlklqvlldeeykqlvkdrkflrevfvdgeanwplpvnirr
iiqnaqqtfhidhtkpsdltikdivlgvkdlqenllvlrgkneiiqnaqrdavtlfccll
rsrlatrrvlqeyrltkqafdwvlsnieaqflrsvvhpgemvgvlaaqsigepatqmtln
tfhfagvaskkvtsgvprlkeilnvaknmktpsltvylepghaadqeqaklirsaiehtt
lksvtiaseiyydpdprstvipedeeiiqlhfslldeeaeqsfdqqspwllrleldraam
ndkdltmgqvgerikqtfkndlfviwsedndekliircrvvrpksldaeteaeedhmlkk
ientmlenitlrgveniervvmmkydrkvpsptgeyvkepewvletdgvnlsevmtvpgi
dptriytnsfidimevlgieagraalykevynviasdgsyvnyrhmallvdvmttqgglt
svtrhgfnrsntgalmrcsfeetveilfeagasaelddcrgvsenvilgqmapigtgafd
vmidees

Sequence, based on observed residues (ATOM records):

>d2e2ia1 e.29.1.2 (A:3-1449) RBP1 {Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
gqqyssaplrtvkevqfglfspeevraisvakirfpetmdetqtrakigglndprlgsid
rnlkcqtcqegmnecpghfghidlakpvfhvgfiakikkvcecvcmhcgkllldehnelm
rqalaikdskkrfaaiwtlcktkmvcetdvpseddptqlvsrggcgntqptirkdglklv
gswkkdratelrvlsteeilnifkhisvkdftslgfnevfsrpewmiltclpvppppvrp
sisfnesqrgeddltfkladilkanisletlehngaphhaieeaesllqfhvatymdndi
agqpqalqksgrpvksirarlkgkegrirgnlmgkrvdfsartvisgdpnleldqvgvpk
siaktltypevvtpynidrltqlvrngpnehpgakyvirdsgdridlryskragdiqlqy
gwkverhimdndpvlfnrqpslhkmsmmahrvkvipystfrlnlsvtspynadfdgdemn
lhvpqseetraelsqlcavplqivspqsnkpcmgivqdtlcgirkltlrdtfieldqvln
mlywvpdwdgviptpaiikpkplwsgkqilsvaipngihlqrfdegttllspkdngmlii
dgqiifgvvekktvgssngglihvvtrekgpqvcaklfgniqkvvnfwllhngfstgigd
tiadgptmreitetiaeakkkvldvtkeaqanlltakhgmtlresfednvvrflneardk
agrlaevnlkdlnnvkqmvmagskgsfiniaqmsacvgqqsvegkriafgfvdrtlphfs
kddyspeskgfvensylrgltpqefffhamggreglidtavktaetgyiqrrlvkaledi
mvhydnttrnslgnviqfiygedgmdaahiekqsldtiggsdaafekryrvdllntdhtl
dpsllesgseilgdlklqvlldeeykqlvkdrkflrevfvdgeanwplpvnirriiqnaq
qtfhidhtkpsdltikdivlgvkdlqenllvlrgkneiiqnaqrdavtlfccllrsrlat
rrvlqeyrltkqafdwvlsnieaqflrsvvhpgemvgvlaaqsigepatqmtlkkvtsgv
prlkeilnvaknmktpsltvylepghaadqeqaklirsaiehttlksvtiaseiyydpdp
rstvipedeeiiqlhfslqqspwllrleldraamndkdltmgqvgerikqtfkndlfviw
sedndekliircrvvaeedhmlkkientmlenitlrgveniervvmmkydrkvpsptgey
vkepewvletdgvnlsevmtvpgidptriytnsfidimevlgieagraalykevynvias
dgsyvnyrhmallvdvmttqggltsvtrhgfnrsntgalmrcsfeetveilfeagasael
ddcrgvsenvilgqmapigtgafdvmidees

Timeline for d2e2ia1:

• d2e2ia1 first appeared in SCOP 1.73
  
• d2e2ia1 appears in SCOPe 2.07