SCOP 1.73: Domain d2e1wa1: 2e1w A:4-352

Lineage for d2e1wa1 (2e1w A:4-352)

1. Root: SCOP 1.73

2. Class c: Alpha and beta proteins (a/b) [51349] (141 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.9: Metallo-dependent hydrolases [51556] (15 families)
   the beta-sheet barrel is similarly distorted and capped by a C-terminal helix
   has transition metal ions bound inside the barrel

5. Family c.1.9.1: Adenosine/AMP deaminase [51557] (2 proteins)

6. Protein Adenosine deaminase (ADA) [51558] (3 species)
   Common fold covers the whole protein structure

7. Species Cow (Bos taurus) [TaxId:9913] [82257] (16 PDB entries)

8. Domain d2e1wa1: 2e1w A:4-352 [131972]
   automatically matched to d1ndva_
   complexed with fr6, zn

Details for d2e1wa1

PDB Entry: 2e1w, 2.5 Å

PDB Description: Crystal structure of adenosine deaminase complexed with potent inhibitors

PDB Compounds: (A:) adenosine deaminase

SCOP Domain Sequences for d2e1wa1:

Sequence; same for both SEQRES and ATOM records:

>d2e1wa1 c.1.9.1 (A:4-352) Adenosine deaminase (ADA) {Cow (Bos taurus) [TaxId: 9913]}
tpafdkpkvelhvhldgaikpetilyygkrrgialpadtpeelqniigmdkpltlpdfla
kfdyympaiagcrdaikriayefvemkakdgvvyvevrysphllanskvepipwnqaegd
ltpdevvslvnqglqegerdfgvkvrsilccmrhqpswssevvelckkyreqtvvaidla
gdetiegsslfpghvqayaeavksgvhrtvhagevgsanvvkeavdtlkterlghgyhtl
edttlynrlrqenmhfeicpwssyltgawkpdtehavirfkndqvnyslntddplifkst
ldtdyqmtkkdmgfteeefkrlninaakssflpedekkelldllykayr

Timeline for d2e1wa1:

• d2e1wa1 is new in SCOP 1.73
  
• d2e1wa1 appears in SCOP 1.75
  
• d2e1wa1 appears in the current release, SCOPe 2.08, called d2e1wa_