SCOPe 2.03: Domain d2e1ra2: 2e1r A:2-343

Lineage for d2e1ra2 (2e1r A:2-343)

1. Root: SCOPe 2.03

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (25 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.8: G proteins [52592] (79 proteins)
   core: mixed beta-sheet of 6 strands, order 231456; strand 2 is antiparallel to the rest

6. Protein Elongation factor 2 (eEF-2), N-terminal (G) domain [82404] (1 species)

7. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [82405] (16 PDB entries)
   Uniprot P32324

8. Domain d2e1ra2: 2e1r A:2-343 [131967]
   Other proteins in same PDB: d2e1ra1, d2e1ra3, d2e1ra4, d2e1ra5
   automatically matched to d1n0vc2
   complexed with gdp, sod

Details for d2e1ra2

PDB Entry: 2e1r, 3.15 Å

PDB Description: structure of eef2 in complex with a sordarin derivative

PDB Compounds: (A:) Elongation factor 2

SCOPe Domain Sequences for d2e1ra2:

Sequence, based on SEQRES records:

>d2e1ra2 c.37.1.8 (A:2-343) Elongation factor 2 (eEF-2), N-terminal (G) domain {Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
vaftvdqmrslmdkvtnvrnmsviahvdhgkstltdslvqragiisaakagearftdtrk
deqergitikstaislysemsdedvkeikqktdgnsflinlidspghvdfssevtaalrv
tdgalvvvdtiegvcvqtetvlrqalgerikpvvvinkvdrallelqvskedlyqtfart
vesvnvivstyadevlgdvqvypargtvafgsglhgwaftirqfatryakkfgvdkakmm
drlwgdsffnpktkkwtnkdtdaegkplerafnmfildpifrlftaimnfkkdeipvlle
kleivlkgdekdlegkallkvvmrkflpaadallemivlhlp

Sequence, based on observed residues (ATOM records):

>d2e1ra2 c.37.1.8 (A:2-343) Elongation factor 2 (eEF-2), N-terminal (G) domain {Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
vaftvdqmrslmdkvtnvrnmsviahvdhgkstltdslvqragiisaakergitikstai
slysemsdedvkeikqktdgnsflinlidspghvdfssevtaalrvtdgalvvvdtiegv
cvqtetvlrqalgerikpvvvinkvdrallelqvskedlyqtfartvesvnvivstyade
vlgdvqvypargtvafgsglhgwaftirqfatryakkfgvdkakmmdrlwgdsffnpktk
kwtnkdtdaegkplerafnmfildpifrlftaimnfkkdeipvllekleivlkgdekdle
gkallkvvmrkflpaadallemivlhlp

Timeline for d2e1ra2:

• d2e1ra2 first appeared in SCOP 1.73
  
• d2e1ra2 appears in SCOPe 2.02
  
• d2e1ra2 appears in SCOPe 2.04
  
• d2e1ra2 appears in the current release, SCOPe 2.08