SCOP 1.73: Domain d2e1fa1: 2e1f A:1142-1235

Lineage for d2e1fa1 (2e1f A:1142-1235)

1. Root: SCOP 1.73

2. Class a: All alpha proteins [46456] (258 folds)

3. Fold a.60: SAM domain-like [47768] (15 superfamilies)
   4-5 helices; bundle of two orthogonally packed alpha-hairpins; involved in the interactions with DNA and proteins

4. Superfamily a.60.8: HRDC-like [47819] (4 families)

5. Family a.60.8.1: HRDC domain from helicases [47820] (2 proteins)

6. Protein Werner syndrome ATP-dependent helicase, WRN [140640] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [140641] (3 PDB entries)

8. Domain d2e1fa1: 2e1f A:1142-1235 [131964]
   automatically matched to 2E1E A:1142-1235
   complexed with cl

Details for d2e1fa1

PDB Entry: 2e1f, 2 Å

PDB Description: Crystal structure of the HRDC Domain of Human Werner Syndrome Protein, WRN

PDB Compounds: (A:) Werner syndrome ATP-dependent helicase

SCOP Domain Sequences for d2e1fa1:

Sequence; same for both SEQRES and ATOM records:

>d2e1fa1 a.60.8.1 (A:1142-1235) Werner syndrome ATP-dependent helicase, WRN {Human (Homo sapiens) [TaxId: 9606]}
qpvisaqeqetqivlygklvearqkhankmdvppailatnkilvdmakmrpttvenvkri
dgvsegkaamlapllevikhfcqtnsvqtdlfss

Timeline for d2e1fa1:

• d2e1fa1 is new in SCOP 1.73
  
• d2e1fa1 appears in SCOP 1.75
  
• d2e1fa1 appears in the current release, SCOPe 2.08, called d2e1fa_