SCOPe 2.03: Domain d2dw5a1: 2dw5 A:113-293

Lineage for d2dw5a1 (2dw5 A:113-293)

1. Root: SCOPe 2.03

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.2: Common fold of diphtheria toxin/transcription factors/cytochrome f [49379] (10 superfamilies)
   sandwich; 9 strands in 2 sheet; greek-key; subclass of immunoglobin-like fold

4. Superfamily b.2.9: Peptidylarginine deiminase Pad4, middle domain [110083] (1 family)
   automatically mapped to Pfam PF08527

5. Family b.2.9.1: Peptidylarginine deiminase Pad4, middle domain [110084] (1 protein)

6. Protein Peptidylarginine deiminase Pad4, middle domain [110085] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [110086] (7 PDB entries)
   Uniprot Q9UM07

8. Domain d2dw5a1: 2dw5 A:113-293 [131805]
   Other proteins in same PDB: d2dw5a2, d2dw5a3
   automatically matched to d1wd8a1
   complexed with bfb, ca, so4

Details for d2dw5a1

PDB Entry: 2dw5, 2.3 Å

PDB Description: Crystal structure of human peptidylarginine deiminase 4 in complex with N-alpha-benzoyl-N5-(2-fluoro-1-iminoethyl)-L-ornithine amide

PDB Compounds: (A:) Protein-arginine deiminase type-4

SCOPe Domain Sequences for d2dw5a1:

Sequence, based on SEQRES records:

>d2dw5a1 b.2.9.1 (A:113-293) Peptidylarginine deiminase Pad4, middle domain {Human (Homo sapiens) [TaxId: 9606]}
veislcaditrtgkvkptravkdqrtwtwgpcgqgaillvncdrdnlessamdceddevl
dsedlqdmslmtlstktpkdfftnhtlvlhvarsemdkvrvfqatrgklsskcsvvlgpk
wpshylmvpggkhnmdfyvealafpdtdfpglitltislldtsnlelpeavvfqdsvvfr
v

Sequence, based on observed residues (ATOM records):

>d2dw5a1 b.2.9.1 (A:113-293) Peptidylarginine deiminase Pad4, middle domain {Human (Homo sapiens) [TaxId: 9606]}
veislcaditrtgkqrtwtwgpcgqgaillvncdrdnlessamdceddevldsedlqdms
lmtlstktpkdfftnhtlvlhvarsemdkvrvfqatcsvvlgpkwpshylmvpggkhnmd
fyvealafpdtdfpglitltislldtsnlelpeavvfqdsvvfrv

Timeline for d2dw5a1:

• d2dw5a1 first appeared in SCOP 1.73
  
• d2dw5a1 appears in SCOPe 2.02
  
• d2dw5a1 appears in SCOPe 2.04
  
• d2dw5a1 appears in the current release, SCOPe 2.08