SCOPe 2.08: Domain d2dr0c1: 2dr0 C:3021-3553

Lineage for d2dr0c1 (2dr0 C:3021-3553)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.69: alpha/beta-Hydrolases [53473] (1 superfamily)
   core: 3 layers, a/b/a; mixed beta-sheet of 8 strands, order 12435678, strand 2 is antiparallel to the rest

4. Superfamily c.69.1: alpha/beta-Hydrolases [53474] (43 families)
   many members have left-handed crossover connection between strand 8 and additional strand 9

5. Family c.69.1.1: Acetylcholinesterase-like [53475] (6 proteins)
   automatically mapped to Pfam PF00135

6. Protein Mammalian carboxylesterase (liver carboxylesterase I) [75282] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [89768] (7 PDB entries)

8. Domain d2dr0c1: 2dr0 C:3021-3553 [131652]
   automatically matched to d1mx9d_
   complexed with nag, sia, so4, tch

Details for d2dr0c1

PDB Entry: 2dr0, 3.2 Å

PDB Description: crystal structure of human carboxylesterase in complex with taurocholate

PDB Compounds: (C:) Liver carboxylesterase 1

SCOPe Domain Sequences for d2dr0c1:

Sequence; same for both SEQRES and ATOM records:

>d2dr0c1 c.69.1.1 (C:3021-3553) Mammalian carboxylesterase (liver carboxylesterase I) {Human (Homo sapiens) [TaxId: 9606]}
ssppvvdtvhgkvlgkfvslegfaqpvaiflgipfakpplgplrftppqpaepwsfvkna
tsyppmctqdpkagqllselftnrkeniplklsedclylniytpadltkknrlpvmvwih
ggglmvgaastydglalaahenvvvvtiqyrlgiwgffstgdehsrgnwghldqvaalrw
vqdniasfggnpgsvtifgesaggesvsvlvlsplaknlfhraisesgvaltsvlvkkgd
vkplaeqiaitagcktttsavmvhclrqkteeellettlkmkflsldlqgdpresqpllg
tvidgmlllktpeelqaernfhtvpymvginkqefgwlipmlmsyplsegqldqktamsl
lwksyplvciakelipeatekylggtddtvkkkdlfldliadvmfgvpsvivarnhrdag
aptymyefqyrpsfssdmkpktvigdhgdelfsvfgapflkegaseeeirlskmvmkfwa
nfarngnpngeglphwpeynqkegylqigantqaaqklkdkevafwtnlfak

Timeline for d2dr0c1:

• d2dr0c1 first appeared in SCOP 1.73
  
• d2dr0c1 appears in SCOPe 2.07