SCOPe 2.07: Domain d2dm6b1: 2dm6 B:1-112,B:295-329

Lineage for d2dm6b1 (2dm6 B:1-112,B:295-329)

1. Root: SCOPe 2.07

2. Class b: All beta proteins [48724] (178 folds)

3. Fold b.35: GroES-like [50128] (2 superfamilies)
   contains barrel, partly opened; n*=4, S*=8; meander

4. Superfamily b.35.1: GroES-like [50129] (3 families)

5. Family b.35.1.2: Alcohol dehydrogenase-like, N-terminal domain [50136] (15 proteins)
   C-terminal domain is alpha/beta (classical Rossmann-fold)

6. Protein Leukotriene b4 12-hydroxydehydrogenase/prostaglandin 15-keto reductase [110175] (1 species)

7. Species Guinea pig (Cavia porcellus) [TaxId:10141] [110176] (4 PDB entries)
   Uniprot Q9EQZ5

8. Domain d2dm6b1: 2dm6 B:1-112,B:295-329 [131569]
   Other proteins in same PDB: d2dm6a2, d2dm6a3, d2dm6b2, d2dm6b3
   automated match to d1v3va1
   complexed with imn, nap, tam

Details for d2dm6b1

PDB Entry: 2dm6, 2 Å

PDB Description: crystal structure of anti-configuration of indomethacin and leukotriene b4 12-hydroxydehydrogenase/15-oxo-prostaglandin 13- reductase complex

PDB Compounds: (B:) NADP-dependent leukotriene B4 12-hydroxydehydrogenase

SCOPe Domain Sequences for d2dm6b1:

Sequence; same for both SEQRES and ATOM records:

>d2dm6b1 b.35.1.2 (B:1-112,B:295-329) Leukotriene b4 12-hydroxydehydrogenase/prostaglandin 15-keto reductase {Guinea pig (Cavia porcellus) [TaxId: 10141]}
mvkakswtlkkhfqgkptqsdfelktvelpplkngevllealflsvdpymriaskrlkeg
avmmgqqvarvvesknsafpagsivlaqsgwtthfisdgkgleklltewpdkXkiqyheh
vtkgfenmpaafiemlnganlgkavvta

Timeline for d2dm6b1:

• d2dm6b1 first appeared in SCOP 1.73
  
• d2dm6b1 appears in SCOPe 2.06
  
• d2dm6b1 appears in the current release, SCOPe 2.08