Lineage for d2dm6a2 (2dm6 A:113-294)

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2090218Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
    The nucleotide-binding modes of this and the next two folds/superfamilies are similar
  4. 2090219Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families) (S)
  5. 2090220Family c.2.1.1: Alcohol dehydrogenase-like, C-terminal domain [51736] (17 protein domains)
    N-terminal all-beta domain defines family
  6. 2090522Protein Leukotriene b4 12-hydroxydehydrogenase/prostaglandin 15-keto reductase [110405] (1 species)
  7. 2090523Species Guinea pig (Cavia porcellus) [TaxId:10141] [110406] (4 PDB entries)
    Uniprot Q9EQZ5
  8. 2090524Domain d2dm6a2: 2dm6 A:113-294 [131568]
    Other proteins in same PDB: d2dm6a1, d2dm6a3, d2dm6b1, d2dm6b3
    automated match to d1v3va2
    complexed with imn, nap, tam

Details for d2dm6a2

PDB Entry: 2dm6 (more details), 2 Å

PDB Description: Crystal structure of anti-configuration of indomethacin and leukotriene B4 12-hydroxydehydrogenase/15-oxo-prostaglandin 13-reductase complex
PDB Compounds: (A:) NADP-dependent leukotriene B4 12-hydroxydehydrogenase

SCOPe Domain Sequences for d2dm6a2:

Sequence; same for both SEQRES and ATOM records: (download)

>d2dm6a2 c.2.1.1 (A:113-294) Leukotriene b4 12-hydroxydehydrogenase/prostaglandin 15-keto reductase {Guinea pig (Cavia porcellus) [TaxId: 10141]}

SCOPe Domain Coordinates for d2dm6a2:

Click to download the PDB-style file with coordinates for d2dm6a2.
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Timeline for d2dm6a2: