SCOPe 2.06: Domain d2dftc_: 2dft C:

Lineage for d2dftc_ (2dft C:)

1. Root: SCOPe 2.06

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (26 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.2: Shikimate kinase (AroK) [52566] (2 proteins)
   similar to the nucleotide/nucleoside kinases but acts on different substrate
   automatically mapped to Pfam PF01202

6. Protein Shikimate kinase (AroK) [52567] (4 species)

7. Species Mycobacterium tuberculosis [TaxId:1773] [75194] (11 PDB entries)
   Uniprot P95014

8. Domain d2dftc_: 2dft C: [131478]
   automated match to d1l4ua_
   complexed with adp, cl, mg

Details for d2dftc_

PDB Entry: 2dft, 2.8 Å

PDB Description: Structure of shikimate kinase from Mycobacterium tuberculosis complexed with ADP and Mg at 2.8 angstrons of resolution

PDB Compounds: (C:) Shikimate kinase

SCOPe Domain Sequences for d2dftc_:

Sequence, based on SEQRES records:

>d2dftc_ c.37.1.2 (C:) Shikimate kinase (AroK) {Mycobacterium tuberculosis [TaxId: 1773]}
apkavlvglpgsgkstigrrlakalgvglldtdvaieqrtgrsiadifatdgeqefrrie
edvvraaladhdgvlslgggavtspgvraalaghtvvyleisaaegvrrtggntvrplla
gpdraekyralmakraplyrrvatmrvdtnrrnpgavvrhilsrl

Sequence, based on observed residues (ATOM records):

>d2dftc_ c.37.1.2 (C:) Shikimate kinase (AroK) {Mycobacterium tuberculosis [TaxId: 1773]}
apkavlvglpgsgkstigrrlakalgvglldtdvaieqrtgrsiadifatdgeqefrrie
edvvraaladhdgvlslgggavtspgvraalaghtvvyleisaaegvrrtggdraekyra
lmakraplyrrvatmrvdtnrrnpgavvrhilsrl

Timeline for d2dftc_:

• d2dftc_ first appeared in SCOP 1.73, called d2dftc1
  
• d2dftc_ appears in SCOPe 2.05
  
• d2dftc_ appears in SCOPe 2.07
  
• d2dftc_ appears in the current release, SCOPe 2.08