SCOP 1.75: Domain d2dfkb1: 2dfk B:1-187

Lineage for d2dfkb1 (2dfk B:1-187)

1. Root: SCOP 1.75

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (24 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.8: G proteins [52592] (78 proteins)
   core: mixed beta-sheet of 6 strands, order 231456; strand 2 is antiparallel to the rest

6. Protein CDC42 [52619] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [52620] (19 PDB entries)

8. Domain d2dfkb1: 2dfk B:1-187 [131473]
   Other proteins in same PDB: d2dfka1, d2dfka2
   automatically matched to d1aje__
   complexed with gol, so4

Details for d2dfkb1

PDB Entry: 2dfk, 2.15 Å

PDB Description: Crystal structure of the CDC42-Collybistin II complex

PDB Compounds: (B:) cell division cycle 42 isoform 1

SCOP Domain Sequences for d2dfkb1:

Sequence, based on SEQRES records:

>d2dfkb1 c.37.1.8 (B:1-187) CDC42 {Human (Homo sapiens) [TaxId: 9606]}
mqtikcvvvgdgavgktcllisyttnkfpseyvptvfdnyavtvmiggepytlglfdtag
qedydrlrplsypqtdvflvcfsvvspssfenvkekwvpeithhcpktpfllvgtqidlr
ddpstieklaknkqkpitpetaeklardlkavkyvecsaltqkglknvfdeailaalepp
epkksrr

Sequence, based on observed residues (ATOM records):

>d2dfkb1 c.37.1.8 (B:1-187) CDC42 {Human (Homo sapiens) [TaxId: 9606]}
mqtikcvvvgdgavgktcllisyttnkfpseyvptvfdnyavtvmiggepytlglfdtag
qedydrlrplsypqtdvflvcfsvvspssfenvkekwvpeithhcpktpfllvgtqidlr
ddpstieklaknkqkpitpetaeklardlkavkyvecsaltqkglknvfdeailaalepk
srr

Timeline for d2dfkb1:

• d2dfkb1 first appeared in SCOP 1.73
  
• d2dfkb1 is called d2dfkb_ in SCOPe 2.01
  
• d2dfkb1 appears in the current release, SCOPe 2.08, called d2dfkb_