SCOP 1.75: Domain d2d41b1: 2d41 B:1-562

Lineage for d2d41b1 (2d41 B:1-562)

1. Root: SCOP 1.75

2. Class e: Multi-domain proteins (alpha and beta) [56572] (66 folds)

3. Fold e.8: DNA/RNA polymerases [56671] (1 superfamily)
   divided into morphological domains including "palm", "thumb" and "fingers"; the catalytic "palm" domain is conserved to all members

4. Superfamily e.8.1: DNA/RNA polymerases [56672] (6 families)
   "palm" domain has a ferredoxin-like fold, related to that of an adenylyl cyclase domain

5. Family e.8.1.4: RNA-dependent RNA-polymerase [56694] (2 proteins)

6. Protein Viral RNA polymerase [56695] (10 species)

7. Species Hepatitis C virus [TaxId:11103] [56697] (21 PDB entries)

8. Domain d2d41b1: 2d41 B:1-562 [131237]
   automatically matched to d1nhvb_
   complexed with snh

Details for d2d41b1

PDB Entry: 2d41, 2.1 Å

PDB Description: X-ray crystal structure of hepatitis C virus RNA-dependent RNA polymerase in complex with non-nucleoside inhibitor

PDB Compounds: (B:) Polyprotein

SCOP Domain Sequences for d2d41b1:

Sequence, based on SEQRES records:

>d2d41b1 e.8.1.4 (B:1-562) Viral RNA polymerase {Hepatitis C virus [TaxId: 11103]}
smsytwtgalitpcaaeesklpinalsnsllrhhnmvyattsrsaglrqkkvtfdrlqvl
ddhyrdvlkemkakastvkakllsveeackltpphsakskfgygakdvrnlsskavnhih
svwkdlledtvtpidttimaknevfcvqpekggrkparlivfpdlgvrvcekmalydvvs
tlpqvvmgssygfqyspgqrveflvntwkskknpmgfsydtrcfdstvtendirveesiy
qccdlapearqaikslterlyiggpltnskgqncgyrrcrasgvlttscgntltcylkas
aacraaklqdctmlvngddlvvicesagtqedaaslrvfteamtrysappgdppqpeydl
elitscssnvsvahdasgkrvyyltrdpttplaraawetarhtpvnswlgniimyaptlw
armilmthffsillaqeqlekaldcqiygacysiepldlpqiierlhglsafslhsyspg
einrvasclrklgvpplrvwrhrarsvrarllsqggraatcgkylfnwavktklkltpip
aasqldlsgwfvagysggdiyh

Sequence, based on observed residues (ATOM records):

>d2d41b1 e.8.1.4 (B:1-562) Viral RNA polymerase {Hepatitis C virus [TaxId: 11103]}
smsytwtgalitpcaaeesklpinalsnsllrhhnmvyattsrsaglrqkkvtfdrlqvl
ddhyrdvlkemkakastvkakllsveeackltpphsakskfgygakdvrnlsskavnhih
svwkdlledtvtpidttimaknevfcvqrkparlivfpdlgvrvcekmalydvvstlpqv
vmgssygfqyspgqrveflvntwkskknpmgfsydtrcfdstvtendirveesiyqccdl
apearqaikslterlyiggpltnskgqncgyrrcrasgvlttscgntltcylkasaacra
aklqdctmlvngddlvvicesagtqedaaslrvfteamtrysappgdppqpeydlelits
cssnvsvahdasgkrvyyltrdpttplaraawetarhtpvnswlgniimyaptlwarmil
mthffsillaqeqlekaldcqiygacysiepldlpqiierlhglsafslhsyspgeinrv
asclrklgvpplrvwrhrarsvrarllsqggraatcgkylfnwavktklkltpipaasql
dlsgwfvagysggdiyh

Timeline for d2d41b1:

• d2d41b1 first appeared in SCOP 1.73
  
• d2d41b1 is called d2d41b_ in SCOPe 2.01
  
• d2d41b1 appears in the current release, SCOPe 2.08, called d2d41b_