SCOPe 2.08: Domain d2d1ya1: 2d1y A:2-249

Lineage for d2d1ya1 (2d1y A:2-249)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families)

5. Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (73 proteins)
   also known as short-chain dehydrogenases and SDR family
   parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7
   has additional subdomain(s) that are not in the common domain
   

6. Protein Hypothetical protein TTHA0369 [141896] (1 species)
   TT0321

7. Species Thermus thermophilus [TaxId:274] [141897] (1 PDB entry)
   Uniprot Q5SLC4 2-249

8. Domain d2d1ya1: 2d1y A:2-249 [131151]
   Other proteins in same PDB: d2d1yb_, d2d1yc_, d2d1yd_
   complexed with nad

Details for d2d1ya1

PDB Entry: 2d1y, 1.65 Å

PDB Description: crystal structure of tt0321 from thermus thermophilus hb8

PDB Compounds: (A:) hypothetical protein TT0321

SCOPe Domain Sequences for d2d1ya1:

Sequence, based on SEQRES records:

>d2d1ya1 c.2.1.2 (A:2-249) Hypothetical protein TTHA0369 {Thermus thermophilus [TaxId: 274]}
glfagkgvlvtggargigraiaqafaregalvalcdlrpegkevaeaiggaffqvdlede
rervrfveeaayalgrvdvlvnnaaiaapgsaltvrlpewrrvlevnltapmhlsalaar
emrkvgggaivnvasvqglfaeqenaaynaskgglvnltrslaldlaplrirvnavapga
iateavleaialspdpertrrdwedlhalrrlgkpeevaeavlflasekasfitgailpv
dggmtasf

Sequence, based on observed residues (ATOM records):

>d2d1ya1 c.2.1.2 (A:2-249) Hypothetical protein TTHA0369 {Thermus thermophilus [TaxId: 274]}
glfagkgvlvtggargigraiaqafaregalvalcdlrpegkevaeaiggaffqvdlede
rervrfveeaayalgrvdvlvnnaaiaapgsaltvrlpewrrvlevnltapmhlsalaar
emrkvgggaivnvasvqglfaeqenaaynaskgglvnltrslaldlaplrirvnavapga
iateavleaiarrdwedlhalrrlgkpeevaeavlflasekasfitgailpvdggmtasf

Timeline for d2d1ya1:

• d2d1ya1 first appeared in SCOP 1.73
  
• d2d1ya1 appears in SCOPe 2.07