Class a: All alpha proteins [46456] (290 folds) |
Fold a.266: Indolic compounds 2,3-dioxygenase-like [140958] (1 superfamily) multihelical; bundle, contains interrupted helices |
Superfamily a.266.1: Indolic compounds 2,3-dioxygenase-like [140959] (3 families) contains heme-dependent enzymes |
Family a.266.1.2: Indoleamine 2,3-dioxygenase-like [140963] (3 proteins) Pfam PF01231; contains extra N-terminal all-alpha subdomain of similar fold to the GST C-terminal domain (47615) |
Protein Indoleamine 2,3-dioxygenase [140966] (1 species) |
Species Human (Homo sapiens) [TaxId:9606] [140967] (2 PDB entries) Uniprot P14902 12-403 |
Domain d2d0ta1: 2d0t A:12-403 [131093] Other proteins in same PDB: d2d0tb_ complexed with hem, nhe, pim |
PDB Entry: 2d0t (more details), 2.3 Å
SCOPe Domain Sequences for d2d0ta1:
Sequence, based on SEQRES records: (download)
>d2d0ta1 a.266.1.2 (A:12-403) Indoleamine 2,3-dioxygenase {Human (Homo sapiens) [TaxId: 9606]} skeyhideevgfalpnpqenlpdfyndwmfiakhlpdliesgqlrerveklnmlsidhlt dhksqrlarlvlgcitmayvwgkghgdvrkvlprniavpycqlskklelppilvyadcvl anwkkkdpnkpltyenmdvlfsfrdgdcskgfflvsllveiaaasaikviptvfkamqmq erdtllkalleiasclekalqvfhqihdhvnpkaffsvlriylsgwkgnpqlsdglvyeg fwedpkefaggsagqssvfqcfdvllgiqqtaggghaaqflqdmrrymppahrnflcsle snpsvrefvlskgdaglreaydacvkalvslrsyhlqivtkyilipasqqpkenktsedp skleakgtggtdlmnflktvrstteksllkeg
>d2d0ta1 a.266.1.2 (A:12-403) Indoleamine 2,3-dioxygenase {Human (Homo sapiens) [TaxId: 9606]} skeyhideevgfalpnpqenlpdfyndwmfiakhlpdliesgqlrerveklnmlsidhlt dhksqrlarlvlgcitmayvwgkghgdvrkvlprniavpycqlskklelppilvyadcvl anwkkkdpnkpltyenmdvlfsfrdgdcskgfflvsllveiaaasaikviptvfkamqmq erdtllkalleiasclekalqvfhqihdhvnpkaffsvlriylsgwkgnpqlsdglvyeg fwedpkefaggsagqssvfqcfdvllgiqqtaggghaaqflqdmrrymppahrnflcsle snpsvrefvlskgdaglreaydacvkalvslrsyhlqivtkyilipasqggtdlmnflkt vrstteksllkeg
Timeline for d2d0ta1: