SCOP 1.73: Domain d2cvqb1: 2cvq B:0-153

Lineage for d2cvqb1 (2cvq B:0-153)

1. Root: SCOP 1.73

2. Class c: Alpha and beta proteins (a/b) [51349] (141 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (12 families)

5. Family c.2.1.5: LDH N-terminal domain-like [51848] (8 proteins)

6. Protein Malate dehydrogenase [51849] (12 species)

7. Species Thermus thermophilus [TaxId:274] [82300] (5 PDB entries)
   identical sequence to that from the Thermus flavus enzyme

8. Domain d2cvqb1: 2cvq B:0-153 [130887]
   Other proteins in same PDB: d2cvqa2, d2cvqb2
   automatically matched to d1iz9a1
   complexed with nap, trs

Details for d2cvqb1

PDB Entry: 2cvq, 2.08 Å

PDB Description: Crystal structure of NAD(H)-dependent malate dehydrogenase complexed with NADPH

PDB Compounds: (B:) malate dehydrogenase

SCOP Domain Sequences for d2cvqb1:

Sequence; same for both SEQRES and ATOM records:

>d2cvqb1 c.2.1.5 (B:0-153) Malate dehydrogenase {Thermus thermophilus [TaxId: 274]}
mkapvrvavtgaagqigysllfriaagemlgkdqpvilqlleipqamkalegvvmeledc
afpllagleatddpkvafkdadyallvgaaprkagmerrdllqvngkifteqgralaeva
kkdvkvlvvgnpantnaliayknapglnprnfta

Timeline for d2cvqb1:

• d2cvqb1 is new in SCOP 1.73
  
• d2cvqb1 appears in SCOP 1.75
  
• d2cvqb1 appears in the current release, SCOPe 2.08