SCOPe 2.06: Domain d2cpra1: 2cpr A:483-593

Lineage for d2cpra1 (2cpr A:483-593)

1. Root: SCOPe 2.06

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.60: SAM domain-like [47768] (16 superfamilies)
   4-5 helices; bundle of two orthogonally packed alpha-hairpins; involved in the interactions with DNA and proteins

4. Superfamily a.60.8: HRDC-like [47819] (5 families)

5. Family a.60.8.4: EXOSC10 HRDC domain-like [140646] (2 proteins)

6. Protein Exosome component 10, EXOSC10 [140649] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [140650] (1 PDB entry)
   Uniprot Q01780 483-595

8. Domain d2cpra1: 2cpr A:483-593 [130705]
   Other proteins in same PDB: d2cpra2, d2cpra3

Details for d2cpra1

PDB Entry: 2cpr

PDB Description: solution structure of the hrdc domain of human exosome component 10

PDB Compounds: (A:) Exosome component 10

SCOPe Domain Sequences for d2cpra1:

Sequence; same for both SEQRES and ATOM records:

>d2cpra1 a.60.8.4 (A:483-593) Exosome component 10, EXOSC10 {Human (Homo sapiens) [TaxId: 9606]}
kpiftdesylelyrkqkkhlntqqltafqllfawrdktarredesygyvlpnhmmlkiae
elpkepqgiiaccnpvpplvrqqinemhlliqqarempllksevaagvkks

Timeline for d2cpra1:

• d2cpra1 first appeared in SCOP 1.73
  
• d2cpra1 appears in SCOPe 2.05
  
• d2cpra1 appears in SCOPe 2.07
  
• d2cpra1 appears in the current release, SCOPe 2.08